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经玻璃化冷冻的成熟人类卵母细胞来源的单个囊胚移植后成功妊娠并分娩。

Successful pregnancy and delivery after transfer of a single blastocyst derived from a vitrified mature human oocyte.

作者信息

Kyono Koichi, Fuchinoue Kohei, Yagi Akiko, Nakajo Yukiko, Yamashita Ayako, Kumagai Shima

机构信息

Department of Gynecology and Urology, Ladies Clinic Kyono, Miyagi, Japan.

出版信息

Fertil Steril. 2005 Oct;84(4):1017. doi: 10.1016/j.fertnstert.2005.04.051.

DOI:10.1016/j.fertnstert.2005.04.051
PMID:16213860
Abstract

OBJECTIVE

To describe the first case of delivery after the transfer of a single blastocyst derived from a vitrified mature human oocyte.

DESIGN

Case report.

SETTING

Private assisted reproduction clinic.

PATIENT(S): A normal 31-year-old woman.

INTERVENTION(S): An unsuccessful attempt was made to extract sperm from the patient's nonobstructive azoospermic husband by testicular sperm extraction.

MAIN OUTCOME MEASURE(S): Transfer of single blastocyst derived from vitrified human oocyte and donor sperm.

RESULT(S): A healthy male neonate weighing 3000 g was born.

CONCLUSION(S): Vitrification is a useful method of preserving mature human oocytes and has the advantage of time-effectiveness, simplicity, cost reduction, and no need for devices such as programmable freezers.

摘要

目的

描述首例由玻璃化冷冻的成熟人类卵母细胞获得的单个囊胚移植后分娩的病例。

设计

病例报告。

地点

私立辅助生殖诊所。

患者

一名31岁的正常女性。

干预措施

尝试通过睾丸取精术从患者非梗阻性无精子症丈夫体内获取精子,但未成功。

主要观察指标

移植由玻璃化冷冻的人类卵母细胞和供体精子获得的单个囊胚。

结果

一名体重3000克的健康男婴出生。

结论

玻璃化冷冻是保存成熟人类卵母细胞的一种有效方法,具有时效性强、操作简单、成本降低且无需程序降温仪等设备的优点。

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