Esposito Katherine, Giugliano Dario
Division of Metabolic Diseases, Policlinico Seconda Università di Napoli, University of Naples, Piazza L. Miraglia, 80138 Naples, Italy.
Eur Heart J. 2006 Jan;27(1):15-20. doi: 10.1093/eurheartj/ehi605. Epub 2005 Oct 11.
Both epidemiological studies and intervention trials support an important role of diet in reducing the risk of a variety of chronic diseases, including cardiovascular disease, and overall mortality. We discuss available evidence indicating that the generation of a pro-inflammatory milieu might be one mechanism through which unhealthy diets are linked to metabolic and cardiovascular diseases. In practical terms, fully understanding the link between diet and inflammation holds the premise to elucidate the mechanisms by which dietary patterns improve cardiovascular health.
流行病学研究和干预试验均支持饮食在降低包括心血管疾病在内的多种慢性疾病风险及总体死亡率方面发挥着重要作用。我们讨论了现有证据,这些证据表明促炎环境的产生可能是不健康饮食与代谢性疾病和心血管疾病相关联的一种机制。实际上,充分理解饮食与炎症之间的联系是阐明饮食模式改善心血管健康机制的前提。