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A supersized list of obesity genes.

作者信息

Hofker Marten, Wijmenga Cisca

出版信息

Nat Genet. 2009 Feb;41(2):139-40. doi: 10.1038/ng0209-139.

DOI:10.1038/ng0209-139

PMID:19174833

Abstract

摘要

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Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.

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Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Nat Genet. 2009 Jan;41(1):25-34. doi: 10.1038/ng.287. Epub 2008 Dec 14.

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

Nat Genet. 2009 Jan;41(1):18-24. doi: 10.1038/ng.274. Epub 2008 Dec 14.

General and abdominal adiposity and risk of death in Europe.

N Engl J Med. 2008 Nov 13;359(20):2105-20. doi: 10.1056/NEJMoa0801891.

Common nonsynonymous variants in PCSK1 confer risk of obesity.

Nat Genet. 2008 Aug;40(8):943-5. doi: 10.1038/ng.177. Epub 2008 Jul 6.

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Nat Genet. 2008 Jun;40(6):768-75. doi: 10.1038/ng.140. Epub 2008 May 4.

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.

Nat Genet. 2008 May;40(5):638-45. doi: 10.1038/ng.120. Epub 2008 Mar 30.

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.

Science. 2007 May 11;316(5826):889-94. doi: 10.1126/science.1141634. Epub 2007 Apr 12.

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma.

Diabetes. 2003 Apr;52(4):910-7. doi: 10.2337/diabetes.52.4.910.

LMNA, encoding lamin A/C, is mutated in partial lipodystrophy.

Nat Genet. 2000 Feb;24(2):153-6. doi: 10.1038/72807.

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A supersized list of obesity genes.

作者信息

Hofker Marten, Wijmenga Cisca

出版信息

Nat Genet. 2009 Feb;41(2):139-40. doi: 10.1038/ng0209-139.

DOI:10.1038/ng0209-139

PMID:19174833

Abstract

摘要

相似文献

A supersized list of obesity genes.

Nat Genet. 2009 Feb;41(2):139-40. doi: 10.1038/ng0209-139.

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

Nat Genet. 2009 Jan;41(1):18-24. doi: 10.1038/ng.274. Epub 2008 Dec 14.

Diabetes-specific genetic effects on obesity traits in American Indian populations: the Strong Heart Family Study.

BMC Med Genet. 2008 Oct 14;9:90. doi: 10.1186/1471-2350-9-90.

Genomics, type 2 diabetes, and obesity.

N Engl J Med. 2010 Dec 9;363(24):2339-50. doi: 10.1056/NEJMra0906948.

Obesity genetics and epigenetics: dissecting causality.

Circ Cardiovasc Genet. 2014 Jun;7(3):395-6. doi: 10.1161/CIRCGENETICS.114.000698.

Whole genome sequence analysis of the TALLYHO/Jng mouse.

BMC Genomics. 2016 Nov 11;17(1):907. doi: 10.1186/s12864-016-3245-6.

Sex-limited genome-wide linkage scan for body mass index in an unselected sample of 933 Australian twin families.

Twin Res Hum Genet. 2005 Dec;8(6):616-32.

Fatty liver and obesity: phenotypically correlated but genetically distinct traits in a mouse model of type 2 diabetes.

Diabetologia. 2007 Aug;50(8):1641-8. doi: 10.1007/s00125-007-0700-6. Epub 2007 Jun 5.

Comprehensive identification of pleiotropic loci for body fat distribution using the NHGRI-EBI Catalog of published genome-wide association studies.

Obes Rev. 2019 Mar;20(3):385-406. doi: 10.1111/obr.12806. Epub 2018 Nov 22.

Genetic studies of common types of obesity: a critique of the current use of phenotypes.

Obes Rev. 2010 Aug;11(8):612-8. doi: 10.1111/j.1467-789X.2010.00734.x. Epub 2010 Mar 24.

引用本文的文献

Maximal Fat Oxidation During Exercise in Healthy Individuals: Lack of Genetic Association with the rs9939609 Polymorphism.

Genes (Basel). 2024 Dec 24;16(1):4. doi: 10.3390/genes16010004.

rs9939609: T>A Variant and Physical Inactivity as Important Risk Factors for Class III Obesity: A Cross-Sectional Study.

Healthcare (Basel). 2024 Apr 4;12(7):787. doi: 10.3390/healthcare12070787.

Gestational Weight Gain: Is the Role of Genetic Variants a Determinant? A Review.

Int J Mol Sci. 2024 Mar 6;25(5):3039. doi: 10.3390/ijms25053039.

Pathogenicity of Airborne Fungal Species Collected from Indoor and Outdoor Public Areas in Tianjin, China.

Pathogens. 2023 Sep 11;12(9):1154. doi: 10.3390/pathogens12091154.

The Development of a Personalised Training Framework: Implementation of Emerging Technologies for Performance.

J Funct Morphol Kinesiol. 2019 May 16;4(2):25. doi: 10.3390/jfmk4020025.

A Combined Effect of Expression Levels of Obesity-Related Genes and Clinical Factors on Cancer Survival Rate.

Biomed Res Int. 2020 Nov 24;2020:8838676. doi: 10.1155/2020/8838676. eCollection 2020.

Eating Behaviours and Food Cravings; Influence of Age, Sex, BMI and Genotype.

Nutrients. 2019 Feb 12;11(2):377. doi: 10.3390/nu11020377.

Association analysis of FTO gene polymorphisms and obesity risk among Egyptian children and adolescents.

Genes Dis. 2017 Jul 4;4(3):170-175. doi: 10.1016/j.gendis.2017.06.002. eCollection 2017 Sep.

Women's beliefs about what causes obesity: variation by race/ethnicity and acculturation in a Washington State sample.

Ethn Health. 2020 Feb;25(2):243-254. doi: 10.1080/13557858.2017.1414156. Epub 2017 Dec 15.

Gene-nutrient interactions and susceptibility to human obesity.

Genes Nutr. 2017 Oct 30;12:29. doi: 10.1186/s12263-017-0581-3. eCollection 2017.

本文引用的文献

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.

Nat Genet. 2009 Feb;41(2):157-9. doi: 10.1038/ng.301. Epub 2009 Jan 18.

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Nat Genet. 2009 Jan;41(1):25-34. doi: 10.1038/ng.287. Epub 2008 Dec 14.

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.

Nat Genet. 2009 Jan;41(1):18-24. doi: 10.1038/ng.274. Epub 2008 Dec 14.

General and abdominal adiposity and risk of death in Europe.

N Engl J Med. 2008 Nov 13;359(20):2105-20. doi: 10.1056/NEJMoa0801891.

Common nonsynonymous variants in PCSK1 confer risk of obesity.

Nat Genet. 2008 Aug;40(8):943-5. doi: 10.1038/ng.177. Epub 2008 Jul 6.

Common variants near MC4R are associated with fat mass, weight and risk of obesity.

Nat Genet. 2008 Jun;40(6):768-75. doi: 10.1038/ng.140. Epub 2008 May 4.

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.

Nat Genet. 2008 May;40(5):638-45. doi: 10.1038/ng.120. Epub 2008 Mar 30.

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.

Science. 2007 May 11;316(5826):889-94. doi: 10.1126/science.1141634. Epub 2007 Apr 12.

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma.

Diabetes. 2003 Apr;52(4):910-7. doi: 10.2337/diabetes.52.4.910.

LMNA, encoding lamin A/C, is mutated in partial lipodystrophy.

Nat Genet. 2000 Feb;24(2):153-6. doi: 10.1038/72807.