与灵长类C型病毒抗原发生反应的天然人类抗体。
Natural human antibodies reactive with primate type-C viral antigens.
作者信息
Kurth R, Teich N M, Weiss R, Oliver R T
出版信息
Proc Natl Acad Sci U S A. 1977 Mar;74(3):1237-41. doi: 10.1073/pnas.74.3.1237.
Abstract
A survey of human sera from healthy individuals revealed the presence of naturally occurring antibodies that react in radioimmunoprecipitation assays with proteins of mammalian type-C viruses. Of 39 sera tested, 100% showed reactivity against baboon endogenous virus, whereas only 49% showed reactivity against simian sarcoma-associated virus. Polyacrylamide gel electrophoresis of immune precipitates revealed one to three bands that comigrate with the virus structural proteins. There were low, but detectable, levels of antibody to the major internal protein of murine leukemia virus, but no activity against the structural proteins of avian sarcoma virus.
摘要
对健康个体的人血清进行的一项调查显示，存在天然产生的抗体，这些抗体在放射免疫沉淀试验中与哺乳动物C型病毒的蛋白质发生反应。在检测的39份血清中，100%显示出对狒狒内源性病毒的反应性，而只有49%显示出对猿猴肉瘤相关病毒的反应性。免疫沉淀物的聚丙烯酰胺凝胶电泳显示出一到三条与病毒结构蛋白迁移率相同的条带。存在低水平但可检测到的针对鼠白血病病毒主要内部蛋白的抗体，但对禽肉瘤病毒的结构蛋白没有活性。
相似文献
1
Natural human antibodies reactive with primate type-C viral antigens.与灵长类C型病毒抗原发生反应的天然人类抗体。
Proc Natl Acad Sci U S A. 1977 Mar;74(3):1237-41. doi: 10.1073/pnas.74.3.1237.
2
Natural antibodies in sera from healthy humans to antigens on surfaces of type C RNA viruses and cells from primates.健康人类血清中针对C型RNA病毒表面抗原及灵长类动物细胞抗原的天然抗体。
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2491-5. doi: 10.1073/pnas.73.7.2491.
3
Autogenous humoral immunity to baboon xenotropic endogenous type C virus.狒狒嗜异性内源性C型病毒的自身体液免疫
J Natl Cancer Inst. 1976 Sep;57(3):561-5. doi: 10.1093/jnci/57.3.561.
4
Immunity to antigens associated with primate C-type oncoviruses in pregnant women.孕妇对与灵长类C型肿瘤病毒相关抗原的免疫性。
Science. 1978 Mar 24;199(4335):1337-40. doi: 10.1126/science.204010.
5
Antigens in preparations of simian sarcoma virus/simian sarcoma-associated virus reacting with human sera in radioimmunoprecipitation assays.在放射免疫沉淀试验中与人类血清发生反应的猿猴肉瘤病毒/猿猴肉瘤相关病毒制剂中的抗原。
Bibl Haematol. 1975 Oct(43):555-8. doi: 10.1159/000399217.
6
Natural and experimentally induced antibodies to defined mammalian type-C virus proteins in primates.灵长类动物中针对特定哺乳动物C型病毒蛋白的天然及实验诱导抗体。
J Natl Cancer Inst. 1975 Dec;55(6):1419-24. doi: 10.1093/jnci/55.6.1419.
7
Primate retroviruses: immunological cross-reactivity between major structural proteins of new and old world primate virus isolates.灵长类逆转录病毒：新旧世界灵长类病毒分离株主要结构蛋白之间的免疫交叉反应性。
J Virol. 1978 Mar;25(3):797-805. doi: 10.1128/JVI.25.3.797-805.1978.
8
Immunological analysis of structural polypeptides of woolly monkey-gibbon ape type C viruses. Expression of woolly monkey helper viral antigens in cells transformed by woolly monkey sarcoma virus.绒毛猴-长臂猿C型病毒结构多肽的免疫学分析。绒毛猴辅助病毒抗原在绒毛猴肉瘤病毒转化细胞中的表达。
Bibl Haematol. 1975 Oct(43):102-9. doi: 10.1159/000399106.
9
Detection and quantification of type C viral proteins in tissues and sera with an enzyme immunoassay.采用酶免疫测定法检测和定量组织及血清中的C型病毒蛋白。
Infect Immun. 1980 Sep;29(3):972-80. doi: 10.1128/iai.29.3.972-980.1980.
10
Natural antibodies in human sera cross-reactive with type C RNA tumor viral P 30.人血清中与C型RNA肿瘤病毒P30交叉反应的天然抗体。
Anticancer Res. 1982 Sep-Oct;2(5):291-6.
引用本文的文献
1
Monitoring for presence of potentially xenotic viruses in recipients of pig islet xenotransplantation.监测猪胰岛异种移植受体中潜在的外来病毒的存在情况。
J Clin Microbiol. 2004 Nov;42(11):5353-6. doi: 10.1128/JCM.42.11.5353-5356.2004.
2
Characterization of the antibody response specific for the human endogenous retrovirus HTDV/HERV-K.针对人类内源性逆转录病毒HTDV/HERV-K的抗体反应特征
J Virol. 1997 Jun;71(6):4581-8. doi: 10.1128/JVI.71.6.4581-4588.1997.
3
Human endogenous retroviruses: nature, occurrence, and clinical implications in human disease.人类内源性逆转录病毒：性质、存在情况及其在人类疾病中的临床意义
Clin Microbiol Rev. 1996 Jan;9(1):72-99. doi: 10.1128/CMR.9.1.72.
4
Natural antibodies to the human T cell lymphoma virus in patients with cutaneous T cell lymphomas.皮肤T细胞淋巴瘤患者体内针对人类T细胞淋巴瘤病毒的天然抗体。
J Exp Med. 1981 Aug 1;154(2):333-46. doi: 10.1084/jem.154.2.333.
5
Human antibodies recognizing the envelope glycoprotein of the baboon endogenous virus BaEV are of heterophil origin.识别狒狒内源性病毒BaEV包膜糖蛋白的人抗体源自嗜异性。
Med Microbiol Immunol. 1981;170(2):135-43. doi: 10.1007/BF02122677.
6
Neurologic syndromes associated with retroviral infections: current views.与逆转录病毒感染相关的神经系统综合征：当前观点
Surv Immunol Res. 1983;2(4):385-93. doi: 10.1007/BF02918456.
7
Heterophile binding of human antibodies to glycoproteins of retroviruses.
Br J Cancer. 1981 Apr;43(4):517-25. doi: 10.1038/bjc.1981.74.
8
Specificity of human antibodies to oncovirus glycoproteins: recognition of antigen by natural antibodies directed against carbohydrate structures.人类抗体对肿瘤病毒糖蛋白的特异性：针对碳水化合物结构的天然抗体对抗原的识别。
Proc Natl Acad Sci U S A. 1980 Mar;77(3):1622-6. doi: 10.1073/pnas.77.3.1622.
9
HEL-12 virus: general considerations.HEL-12病毒：一般考虑因素。
Surv Immunol Res. 1983;2(1):12-24. doi: 10.1007/BF02918392.
10
Humans have antibodies capable of recognizing oncoviral glycoproteins: demonstration that these antibodies are formed in response to cellular modification of glycoproteins rather than as consequence of exposure to virus.人类拥有能够识别肿瘤病毒糖蛋白的抗体：证明这些抗体是因糖蛋白的细胞修饰而形成，而非接触病毒的结果。
Proc Natl Acad Sci U S A. 1980 Mar;77(3):1617-21. doi: 10.1073/pnas.77.3.1617.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.在噬菌体T4头部组装过程中结构蛋白的切割
Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
3
Induction of tumors in marmoset monkeys by simian sarcoma virus, type 1 (Lagothrix): a preliminary report.1型猿猴肉瘤病毒（绒毛猴属）诱发狨猴肿瘤：初步报告。
J Natl Cancer Inst. 1971 Nov;47(5):1115-20.
4
Evolution of type C viral genes: I. Nucleic acid from baboon type C virus as a measure of divergence among primate species.C型病毒基因的进化：I. 来自狒狒C型病毒的核酸作为灵长类物种间差异的一种衡量指标。
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4513-8. doi: 10.1073/pnas.71.11.4513.
5
Type-C RNA virus gene expression in human tissue.人组织中的C型RNA病毒基因表达。
J Virol. 1974 Dec;14(6):1584-96. doi: 10.1128/JVI.14.6.1584-1596.1974.
6
Failure to detect, in human sera, antibodies cross-reactive with group-specific antigens of murine leukemia virus.未能在人血清中检测到与鼠白血病病毒群特异性抗原发生交叉反应的抗体。
J Natl Cancer Inst. 1974 May;52(5):1409-13. doi: 10.1093/jnci/52.5.1409.
7
Autogenous immunity to endogenous RNA tumor virus. Identification of antibody reactivity to select viral antigens.对内源性RNA肿瘤病毒的自身免疫。对选定病毒抗原的抗体反应性鉴定。
J Exp Med. 1974 Jun 1;139(6):1568-81. doi: 10.1084/jem.139.6.1568.
8
Antibodies to simian C-type virus antigen in sera of gibbons (Hylobates sp.).长臂猿（长臂猿属）血清中抗猿猴C型病毒抗原的抗体。
Nat New Biol. 1973 Nov 28;246(152):105-7. doi: 10.1038/newbio246105a0.
9
Forssman antigen exposed on surface membrane after viral transformation.病毒转化后暴露于表面膜上的福斯曼抗原。
Nat New Biol. 1971 May 26;231(21):125-6. doi: 10.1038/newbio231125a0.
10
Properties of an oncornavirus glycoprotein: evidence for its presence on the surface of virions and infected cells.一种肿瘤病毒糖蛋白的特性：关于其存在于病毒粒子和受感染细胞表面的证据。
Virology. 1973 Oct;55(2):464-75. doi: 10.1016/0042-6822(73)90188-8.
Zotero 插件