Corner E J, Bruce V M, McDonald B E
Department of Foods and Nutrition, University of Manitoba, Winnipeg, Canada.
Lipids. 1990 Oct;25(10):598-601. doi: 10.1007/BF02536008.
The metabolism of alpha-linolenic acid from canola oil was studied in eight normolipidemic men. The 42-day study was divided into three periods: a 6-day pre-experimental and two 18-day experimental. Approximately 75% of the dietary fat (28% of total energy) was provided by a mixture of fats during the pre-experimental period and either canola oil (CO) or sunflower oil (SO) during the experimental periods. The CO and SO diets were fed in a cross-over design. The ratios of linoleic to linolenic acid were 2.6:1 and 73.9:1 in the CO and SO diets, respectively. Dietary fat source had an effect on plasma phospholipid fatty acids: 18:1n-9, 18:3n-3 and 20:5n-3 were higher (p less than 0.05), and 18:2n-6 was lower in the phosphatidylcholine fraction; 18:1n-9 was higher and 20:4n-6 lower in the phosphatidyl-ethanolamine fraction; and 18:1n-9 and 20:5n-3 were higher and 20:4n-6 and 22:6n-3 were lower in the alkenylacyl ethanolamine phospholipid fraction on the CO diet as compared to the SO diet. Consumption of the canola oil diet resulted in higher n-3 fatty acid levels and lower n-6 fatty acid levels in plasma phospholipids than consumption of the sunflower oil diet.
在八名血脂正常的男性中研究了菜籽油中α-亚麻酸的代谢情况。这项为期42天的研究分为三个阶段：6天的实验前期和两个18天的实验期。在实验前期，约75%的膳食脂肪（占总能量的28%）由多种脂肪混合提供，而在实验期则由菜籽油（CO）或葵花籽油（SO）提供。CO组和SO组饮食采用交叉设计。CO组和SO组饮食中，亚油酸与亚麻酸的比例分别为2.6:1和73.9:1。膳食脂肪来源对血浆磷脂脂肪酸有影响：在磷脂酰胆碱组分中，18:1n-9、18:3n-3和20:5n-3含量较高（p<0.05），而18:2n-6含量较低；在磷脂酰乙醇胺组分中，18:1n-9含量较高，20:4n-6含量较低；与SO组饮食相比，CO组饮食的烯基酰基乙醇胺磷脂组分中18:1n-9和20:5n-3含量较高，20:4n-6和22:6n-3含量较低。与食用葵花籽油饮食相比，食用菜籽油饮食导致血浆磷脂中n-3脂肪酸水平较高，n-6脂肪酸水平较低。
