新型人类鼻病毒及其在哮喘加重和气道重塑中的意义。
New human rhinovirus species and their significance in asthma exacerbation and airway remodeling.
机构信息
Pediatric Pulmonary, Allergy and Immunology, Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt Children's Hospital, 11215 Doctors' Office Tower, 2200 Children's Way, Nashville, TN 37232-9500, USA.
出版信息
Immunol Allergy Clin North Am. 2010 Nov;30(4):541-52, vii. doi: 10.1016/j.iac.2010.08.007. Epub 2010 Sep 24.
Abstract
Asthma is the most common chronic disease of childhood, affecting 10% to 15% of all children. Several different stimuli including allergens, tobacco smoke, certain drugs, and viral or bacterial infections are known to exacerbate asthma symptoms. Among these triggers, viruses are frequent inducers of asthma exacerbations, with human rhinoviruses being the most common in children and adults. This article describes the different species of this virus and their roles as major triggers of asthma exacerbations.
摘要
哮喘是儿童最常见的慢性疾病，影响所有儿童的 10%至 15%。已知有几种不同的刺激物，包括过敏原、烟草烟雾、某些药物和病毒或细菌感染，可使哮喘症状恶化。在这些诱因中，病毒是哮喘恶化的常见诱因，人类鼻病毒在儿童和成人中最为常见。本文描述了这种病毒的不同种属及其作为哮喘恶化主要诱因的作用。
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本文引用的文献
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Pediatr Infect Dis J. 2010 Aug;29(8):717-20. doi: 10.1097/INF.0b013e3181d7a708.
2
Newly identified human rhinoviruses: molecular methods heat up the cold viruses.新发现的人类鼻病毒：分子方法使冷病毒升温。
Rev Med Virol. 2010 May;20(3):156-76. doi: 10.1002/rmv.644.
3
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J Clin Virol. 2010 Mar;47(3):219-23. doi: 10.1016/j.jcv.2010.01.001. Epub 2010 Jan 27.
4
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