在限制温度下3型脊髓灰质炎病毒非衣壳蛋白2的蛋白水解作用：非衣壳蛋白2的分解与RNA合成的丧失相关。
Proteolysis of noncapsid protein 2 of type 3 poliovirus at the restrictive temperature: breakdown of noncapsid protein 2 correlates with loss of RNA synthesis.
作者信息
Bowles S A, Tershak D R
出版信息
J Virol. 1978 Aug;27(2):443-8. doi: 10.1128/JVI.27.2.443-448.1978.
Abstract
Inhibition of RNA synthesis of the LH strain of type 3 poliovirus at the restrictive temperature occurs concurrently with the breakdown of noncapsid virus-specific peptide 2. This finding, along with other reported data (B.D. Korant, In Proteases and Biological Control, p. 621-644, 1975), suggests that noncapsid virus-specific peptide 2 is a component of the viral replicase.
摘要
在限制温度下，3型脊髓灰质炎病毒LH株的RNA合成受到抑制，同时非衣壳病毒特异性肽2发生降解。这一发现，连同其他已报道的数据（B.D.科兰特，《蛋白酶与生物控制》，第621 - 644页，1975年）表明，非衣壳病毒特异性肽2是病毒复制酶的一个组成部分。
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