Suppr超能文献

对活体视网膜中的单细胞进行成像。

Imaging single cells in the living retina.

作者信息

Williams David R

机构信息

Center for Visual Science, William G. Allyn Professor of Medical Optics, University of Rochester, Rochester, NY 14627-0270, United States.

出版信息

Vision Res. 2011 Jul 1;51(13):1379-96. doi: 10.1016/j.visres.2011.05.002. Epub 2011 May 10.

Abstract

A quarter century ago, we were limited to a macroscopic view of the retina inside the living eye. Since then, new imaging technologies, including confocal scanning laser ophthalmoscopy, optical coherence tomography, and adaptive optics fundus imaging, transformed the eye into a microscope in which individual cells can now be resolved noninvasively. These technologies have enabled a wide range of studies of the retina that were previously impossible.

摘要

四分之一个世纪以前,我们对活眼内视网膜的观察还局限于宏观层面。从那时起,包括共焦扫描激光检眼镜、光学相干断层扫描和自适应光学眼底成像在内的新型成像技术,将眼睛变成了一台显微镜,现在可以在不进行侵入性操作的情况下分辨出单个细胞。这些技术使得以前无法开展的一系列视网膜研究成为可能。

相似文献

1
Imaging single cells in the living retina.
Vision Res. 2011 Jul 1;51(13):1379-96. doi: 10.1016/j.visres.2011.05.002. Epub 2011 May 10.
2
Adaptive optics retinal imaging: emerging clinical applications.
Optom Vis Sci. 2010 Dec;87(12):930-41. doi: 10.1097/OPX.0b013e3181ff9a8b.
4
Foveal cone count reduction in resolved endophthalmitis: an adaptive optics scanning laser ophthalmoscopy (AO-SLO)-based prospective pilot study.
Br J Ophthalmol. 2021 Nov;105(11):1520-1524. doi: 10.1136/bjophthalmol-2020-317309. Epub 2020 Sep 11.
5
Adaptive optics ophthalmoscopy: results and applications.
J Refract Surg. 2005 Sep-Oct;21(5):S570-4. doi: 10.3928/1081-597X-20050901-29.
6
Retinal Vascular Diseases Highlighted by Adaptive Optics Ophthalmoscopy.
Rom J Ophthalmol. 2025 Jan-Mar;69(1):36-41. doi: 10.22336/rjo.2025.07.
8
Alterations to the Foveal Cone Mosaic of Diabetic Patients.
Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3395-3403. doi: 10.1167/iovs.17-21793.
9
Imaging the photoreceptor mosaic with adaptive optics: beyond counting cones.
Adv Exp Med Biol. 2012;723:451-8. doi: 10.1007/978-1-4614-0631-0_57.
10
CONE PHOTORECEPTOR INTEGRITY ASSESSED WITH ADAPTIVE OPTICS IMAGING AFTER LASER POINTER-INDUCED RETINAL INJURY.
Retin Cases Brief Rep. 2022 Sep 1;16(5):586-592. doi: 10.1097/ICB.0000000000001025.

引用本文的文献

1
Axicons for improved resolution and depth of focus in adaptive optics scanning light ophthalmoscopy.
Biomed Opt Express. 2025 Jul 16;16(8):3172-3193. doi: 10.1364/BOE.564398. eCollection 2025 Aug 1.
2
Visible-light optical coherence tomography and its applications.
Neurophotonics. 2025 Apr;12(2):020601. doi: 10.1117/1.NPh.12.2.020601. Epub 2025 Apr 9.
6
Ultrahigh-speed multimodal adaptive optics system for microscopic structural and functional imaging of the human retina.
Biomed Opt Express. 2022 Oct 17;13(11):5860-5878. doi: 10.1364/BOE.462594. eCollection 2022 Nov 1.
7
Adaptive Optics Imaging of Inherited Retinal Disease.
Cold Spring Harb Perspect Med. 2023 Jul 5;13(7):a041285. doi: 10.1101/cshperspect.a041285.
8

本文引用的文献

1
Noninvasive imaging of the human rod photoreceptor mosaic using a confocal adaptive optics scanning ophthalmoscope.
Biomed Opt Express. 2011 Jul 1;2(7):1864-76. doi: 10.1364/BOE.2.001864. Epub 2011 Jun 8.
2
Reflective afocal broadband adaptive optics scanning ophthalmoscope.
Biomed Opt Express. 2011 Jun 1;2(6):1757-68. doi: 10.1364/BOE.2.001757. Epub 2011 May 27.
5
Optical properties of the mouse eye.
Biomed Opt Express. 2011 Feb 28;2(4):717-38. doi: 10.1364/BOE.2.000717.
6
Noninvasive measurements and analysis of blood velocity profiles in human retinal vessels.
Invest Ophthalmol Vis Sci. 2011 Jun 13;52(7):4151-7. doi: 10.1167/iovs.10-6940.
7
Imaging light responses of targeted neuron populations in the rodent retina.
J Neurosci. 2011 Feb 23;31(8):2855-67. doi: 10.1523/JNEUROSCI.6064-10.2011.
8
Adaptive optics and the eye (super resolution OCT).
Eye (Lond). 2011 Mar;25(3):321-30. doi: 10.1038/eye.2011.1.
9
Imaging retinal mosaics in the living eye.
Eye (Lond). 2011 Mar;25(3):301-8. doi: 10.1038/eye.2010.221.
10
Images of photoreceptors in living primate eyes using adaptive optics two-photon ophthalmoscopy.
Biomed Opt Express. 2010 Dec 17;2(1):139-48. doi: 10.1364/BOE.2.000139.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验