Bleumink-Pluym N, ter Laak E A, van der Zeijst B A
Department of Bacteriology, School of Veterinary Medicine, University of Utrecht, The Netherlands.
J Clin Microbiol. 1990 Sep;28(9):2012-6. doi: 10.1128/jcm.28.9.2012-2016.1990.
Contagious equine metritis (CEM), a sexually transmitted bacterial disease, was first described in thoroughbred horses. It also occurs in nonthoroughbred horses, in which it produces isolated, apparently unrelated outbreaks. Thirty-two strains of Taylorella equigenitalis, the causative agent of CEM, from all over the world were characterized by field inversion gel electrophoresis of fragments of genomic DNA obtained by digestion with low-cleavage-frequency restriction enzymes. This resulted in a division into five clearly distinct groups. Strains from thoroughbred horses from all continents belonged to one group. Strains from nonthoroughbred horses from various countries were different from strains from thoroughbred horses; four groups could be determined. Two groups contained both streptomycin-resistant and streptomycin-susceptible strains. The data indicate that CEM in nonthoroughbreds did not originate from the thoroughbred population; also, the reverse was not demonstrated. Thus, extensive international transportation directives regarding the testing of nonthoroughbred horses for CEM may need reconsideration.
马传染性子宫炎（CEM）是一种性传播细菌性疾病，最初在纯种马中被发现。它也发生在非纯种马中，并在这些马匹中引发孤立的、看似不相关的疫情。通过用低切割频率限制酶消化获得的基因组DNA片段进行脉冲场凝胶电泳，对来自世界各地的32株马生殖道泰勒菌（CEM的病原体）进行了特征分析。这导致它们被分为五个明显不同的组。来自各大洲纯种马的菌株属于一组。来自不同国家非纯种马的菌株与纯种马的菌株不同，可以确定为四组。两组中同时包含对链霉素耐药和敏感的菌株。数据表明，非纯种马中的CEM并非源自纯种马群体；同样，也未证明相反的情况。因此，关于对非纯种马进行CEM检测的广泛国际运输指令可能需要重新考虑。
