Department of Orthopaedics, The Second Xiangya Hospital of Central South University, Middle Ren-Min Road No. 139, Changsha, Hunan, 410011, China.
Cytotechnology. 2011 Oct;63(5):437-43. doi: 10.1007/s10616-011-9367-4. Epub 2011 Jul 12.
Nanotechnology has emerged to be one of the most powerful engineering approaches in the past half a century. Nanotechnology brought nanomaterials for biomedical use with diverse applications. In the present manuscript we summarize the recent progress in adopting nanobiomaterials for bone healing and repair approaches. We first discuss the use of nanophase surface modification in manipulating metals and ceramics for bone implantation, and then the use of polymers as nanofiber scaffolds in bone repair. Finally we briefly present the potential use of the nanoparticle delivery system as adjunct system in promoting bone regeneration following fracture.
纳米技术是过去半个世纪最强大的工程方法之一。纳米技术带来了用于生物医学用途的纳米材料，具有多种应用。在本手稿中，我们总结了采用纳米生物材料进行骨愈合和修复方法的最新进展。我们首先讨论了纳米相表面改性在操纵金属和陶瓷用于骨植入中的应用，然后讨论了聚合物作为纳米纤维支架在骨修复中的应用。最后，我们简要介绍了纳米颗粒输送系统作为骨折后促进骨再生的辅助系统的潜在用途。
