Padala Kalpana P, Padala Prasad R, Malloy Timothy R, Geske Jenenne A, Dubbert Patricia M, Dennis Richard A, Garner Kimberly K, Bopp Melinda M, Burke William J, Sullivan Dennis H
Reynolds Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
J Aging Res. 2012;2012:597573. doi: 10.1155/2012/597573. Epub 2012 Jun 13.
Objectives. To determine the effects on balance and gait of a Wii-Fit program compared to a walking program in subjects with mild Alzheimer's dementia (AD). Methods. A prospective randomized (1 : 1) pilot study with two intervention arms was conducted in an assisted living facility with twenty-two mild AD subjects. In both groups the intervention occurred under supervision for 30 minutes daily, five times a week for eight weeks. Repeated measures ANOVA and paired t-tests were used to analyze changes. Results. Both groups showed improvement in Berg Balance Scale (BBS), Tinetti Test (TT) and Timed Up and Go (TUG) over 8 weeks. However, there was no statistically significant difference between the groups over time. Intragroup analysis in the Wii-Fit group showed significant improvement on BBS (P = 0.003), and TT (P = 0.013). The walking group showed a trend towards improvement on BBS (P = 0.06) and TUG (P = 0.07) and significant improvement in TT (P = 0.06). Conclusion. This pilot study demonstrates the safety and efficacy of Wii-Fit in an assisted living facility in subjects with mild AD. Use of Wii-Fit resulted in significant improvements in balance and gait comparable to those in the robust monitored walking program. These results need to be confirmed in a larger, methodologically sound study.
目的。确定与步行项目相比,Wii Fit项目对轻度阿尔茨海默病(AD)患者平衡能力和步态的影响。方法。在一家辅助生活设施中,对22名轻度AD患者进行了一项前瞻性随机(1∶1)试点研究,设有两个干预组。两组的干预均在监督下进行,每天30分钟,每周5次,共8周。采用重复测量方差分析和配对t检验分析变化情况。结果。两组在8周内的伯格平衡量表(BBS)、Tinetti测试(TT)和定时起立行走测试(TUG)均有改善。然而,随着时间推移,两组之间无统计学显著差异。Wii Fit组的组内分析显示,BBS(P = 0.003)和TT(P = 0.013)有显著改善。步行组在BBS(P = 0.06)和TUG(P = 0.07)方面有改善趋势,在TT方面有显著改善(P = 0.06)。结论。这项试点研究证明了Wii Fit在辅助生活设施中对轻度AD患者的安全性和有效性。使用Wii Fit导致平衡能力和步态有显著改善,与严格监测的步行项目相当。这些结果需要在一项更大规模、方法合理的研究中得到证实。