Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Curr Hypertens Rep. 2012 Oct;14(5):388-96. doi: 10.1007/s11906-012-0296-1.
The Dietary Approaches to Stop Hypertension (DASH) trial showed that a diet rich in fruits, vegetables, low-fat dairy products with reduced total and saturated fat, cholesterol, and sugar-sweetened products effectively lowers blood pressure in individuals with prehypertension and stage I hypertension. Limited evidence is available on the safety and efficacy of the DASH eating pattern in special patient populations that were excluded from the trial. Caution should be exercised before initiating the DASH diet in patients with chronic kidney disease, chronic liver disease, and those who are prescribed renin-angiotensin-aldosterone system antagonist, but these conditions are not strict contraindications to DASH. Modifications to the DASH diet may be necessary to facilitate its use in patients with chronic heart failure, uncontrolled diabetes mellitus type II, lactose intolerance, and celiac disease. In general, the DASH diet can be adopted by most patient populations and initiated simultaneously with medication therapy and other lifestyle interventions.
膳食防治高血压(DASH)试验表明,富含水果、蔬菜、低脂乳制品(减少总脂肪和饱和脂肪、胆固醇和含糖饮料)的饮食可有效降低高血压前期和 1 期高血压患者的血压。在该试验中被排除的特殊患者人群中,关于 DASH 饮食模式的安全性和有效性的证据有限。在开始 DASH 饮食之前,应谨慎对待慢性肾脏病、慢性肝病以及正在服用肾素-血管紧张素-醛固酮系统拮抗剂的患者,但这些情况并非 DASH 的严格禁忌证。可能需要对 DASH 饮食进行调整,以方便在患有慢性心力衰竭、未控制的 2 型糖尿病、乳糖不耐受和乳糜泻的患者中使用。一般来说,DASH 饮食可被大多数患者人群采用,并可与药物治疗和其他生活方式干预同时开始。