Buddhist Dalin Tzu Chi General Hospital, Chiayi, Taiwan.
BMC Public Health. 2012 Aug 16;12:666. doi: 10.1186/1471-2458-12-666.
Short sleep duration has been reported to associate with increased insulin resistance. However, no studies have investigated whether such association exists in vegetarians. The aim of this study was to investigate the association between sleep duration and insulin resistance in Taiwanese vegetarians.
A total of 1290 individuals were recruited from a regional hospital in south Taiwan during their regular routine physical examination. Only individuals who described themselves as Buddhist vegetarians were included in the study. Demographic information and clinical characteristics were collected and multiple logistic regression analysis was used to evaluate the association between sleep duration and insulin resistance.
A total of 433 vegetarians were included in the study. Results from univariate logistic regression indicated that insulin resistance was significantly associated with male sex, greater waist circumference, higher triglyceride levels, lower high-density lipoprotein cholesterol levels, higher plasma creatinine levels, higher alanine transaminase levels, greater energy expenditure, and sleep duration of more than 8 hours per night. Multiple logistic regression revealed that insulin resistance was significantly and independently associated with sleep duration of more than 8 hours per night (odd ratios = 2.27, 95% confidence interval = 1.24, 4.11) after adjusting for waist circumference and levels of alanine transaminase.
Sleep duration of more than 8 hours per night is an independent risk factor associated with increased insulin resistance in vegetarians.
已有研究报道，睡眠时间过短与胰岛素抵抗有关。然而，目前尚无研究调查这种关联是否存在于素食者中。本研究旨在探讨台湾素食者的睡眠时间与胰岛素抵抗之间的关系。
研究共纳入了 1290 名来自台湾南部某地区医院的体检者。仅纳入自述为佛教素食者的个体。收集了人口统计学信息和临床特征，并采用多因素 logistic 回归分析评估了睡眠时间与胰岛素抵抗之间的关系。
本研究共纳入了 433 名素食者。单因素 logistic 回归分析结果表明，胰岛素抵抗与男性、更大的腰围、更高的甘油三酯水平、更低的高密度脂蛋白胆固醇水平、更高的血浆肌酐水平、更高的丙氨酸氨基转移酶水平、更高的能量消耗以及每晚睡眠时间超过 8 小时有关。多因素 logistic 回归分析显示，在校正腰围和丙氨酸氨基转移酶水平后，每晚睡眠时间超过 8 小时与胰岛素抵抗显著相关（比值比=2.27，95%置信区间=1.24，4.11）。
每晚睡眠时间超过 8 小时是素食者中与胰岛素抵抗增加相关的独立危险因素。
