Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Am J Clin Nutr. 2012 Oct;96(4):735-47. doi: 10.3945/ajcn.112.037119. Epub 2012 Aug 29.
Some intervention studies have suggested that dairy products may influence body weight, but the results remain controversial.
We identified and quantified the effects of dairy consumption on body weight and fat mass from randomized controlled trials (RCTs).
We conducted a comprehensive search of PubMed and EMBASE databases (to April 2012) of English reports of RCTs regarding dairy consumption on body weight, body fat, or body weight and body fat in adults. The results across studies were pooled by using a random-effects meta-analysis.
Twenty-nine RCTs were included with a total of 2101 participants. Overall, consumption of dairy products did not result in a significant reduction in weight (-0.14 kg; 95% CI: -0.66, 0.38 kg; I² = 86.3%). In subgroup analysis, consumption of dairy products reduced body weight in the context of energy restriction or short-term intervention (<1 y) trials but had the opposite effect in ad libitum dietary interventions or long-term trials (≥1 y). Twenty-two RCTs that reported results on body fat showed a modest reduction in the dairy group (-0.45 kg; 95% CI: -0.79, -0.11 kg; I² = 70.9%), and further stratified analysis indicated significant beneficial effects of dairy intervention on body fat in energy-restricted or short-term trials but not in long-term or ad libitum studies.
This meta-analysis does not support the beneficial effect of increasing dairy consumption on body weight and fat loss in long-term studies or studies without energy restriction. However, dairy products may have modest benefits in facilitating weight loss in short-term or energy-restricted RCTs.
一些干预研究表明,乳制品可能会影响体重,但结果仍存在争议。
我们从随机对照试验(RCT)中确定并量化了乳制品摄入对体重和体脂肪的影响。
我们对英文的 RCT 报告进行了全面的 PubMed 和 EMBASE 数据库检索(截至 2012 年 4 月),这些报告涉及乳制品对成年人的体重、体脂肪或体重和体脂肪的影响。使用随机效应荟萃分析对研究结果进行汇总。
共纳入 29 项 RCT,总计 2101 名参与者。总体而言,乳制品的摄入并没有显著减轻体重(-0.14kg;95%CI:-0.66,0.38kg;I²=86.3%)。在亚组分析中,在能量限制或短期干预(<1 年)试验中,乳制品的摄入减少了体重,但在自由饮食干预或长期试验(≥1 年)中则有相反的效果。22 项报告了体脂肪结果的 RCT 显示,乳制品组的体脂肪有适度减少(-0.45kg;95%CI:-0.79,-0.11kg;I²=70.9%),进一步分层分析表明,在能量限制或短期试验中,乳制品干预对体脂肪有显著的有益效果,但在长期或自由饮食研究中则没有。
本荟萃分析不支持在长期研究或无能量限制的研究中增加乳制品摄入对体重和体脂减少的有益作用。然而,乳制品可能在短期或能量限制的 RCT 中适度促进体重减轻。