Center for Sleep and Cognition, Department of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215-5400, USA.
Curr Opin Neurobiol. 2013 Oct;23(5):847-53. doi: 10.1016/j.conb.2013.04.002. Epub 2013 Apr 22.
It would be nice if we could talk about sleep and memory as if there were only one type of memory and one type of sleep. But this is far from the case. Sleep and memory each comes in many forms, and furthermore, memories can go through multiple forms of post-encoding processing that must be individually addressed. Finally, sleep stages per se do not affect memories. Rather, the neuromodulatory and electrophysiological events that characterize these sleep stages must mediate sleep-dependent memory processing. In this review, we attempt to parse out the relative contributions and interactions of these often frustratingly complex systems.
如果我们能够将睡眠和记忆视为只有一种类型的记忆和一种类型的睡眠来讨论,那将是一件好事。但事实远非如此。睡眠和记忆各自都有多种形式,此外,记忆可以经历多种形式的编码后处理,这些处理都必须单独解决。最后,睡眠阶段本身并不影响记忆。相反,这些睡眠阶段的神经调制和电生理事件必须介导睡眠依赖的记忆处理。在这篇综述中,我们试图分析这些常常令人沮丧地复杂系统的相对贡献和相互作用。