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富含血小板血浆能否提高移植脂肪的存活率?最新综述。

Does platelet-rich plasma enhance the survival of grafted fat? An update review.

作者信息

Jin Rong, Zhang Lu, Zhang Yu-Guang

机构信息

Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine Shanghai 200011, China.

出版信息

Int J Clin Exp Med. 2013 Apr 12;6(4):252-8. Print 2013.

PMID:23641301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3631549/
Abstract

Autologous fat grafting enables repair and augmentation of soft tissues and is increasingly used in plastic and reconstructive surgery. The main limitation of fat grafting is unpredictable graft resorption. To obviate this disadvantage, several studies have searched for new ways of increasing the viability of the transplanted tissue. One promising approach has been to mix the fat graft with Platelet-Rich Plasma (PRP) before transplantation. The purpose of this article is to review systematically the available comparative evidence about PRP-assisted fat grafting.

摘要

自体脂肪移植能够修复和增加软组织,并且在整形和重建手术中越来越常用。脂肪移植的主要局限性是移植脂肪吸收不可预测。为了消除这一缺点,多项研究探索了提高移植组织存活率的新方法。一种有前景的方法是在移植前将脂肪移植物与富血小板血浆(PRP)混合。本文的目的是系统回顾关于PRP辅助脂肪移植的现有比较证据。

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本文引用的文献

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Breast reconstruction with autologous fat graft mixed with platelet-rich plasma.采用富含血小板血浆混合自体脂肪移植进行乳房重建。
Surg Innov. 2013 Aug;20(4):370-6. doi: 10.1177/1553350612458544. Epub 2012 Sep 10.
2
Breast fat grafting with platelet-rich plasma: a comparative clinical study and current state of the art.富血小板血浆的乳房脂肪移植:一项比较性临床研究及现状。
Plast Reconstr Surg. 2011 Jun;127(6):2176-2185. doi: 10.1097/PRS.0b013e3182139fe7.
3
Activated platelet-rich plasma improves fat graft survival in nude mice: a pilot study.富血小板血浆激活物可提高裸鼠脂肪移植物的存活率:一项初步研究。
Dermatol Surg. 2011 May;37(5):619-25. doi: 10.1111/j.1524-4725.2011.01953.x. Epub 2011 Apr 14.
4
Influence of platelet-rich plasma on the histologic characteristics of the autologous fat graft to the upper lip of rabbits.富血小板血浆对兔自体脂肪移植至上唇的组织学特征的影响。
Aesthetic Plast Surg. 2011 Aug;35(4):480-6. doi: 10.1007/s00266-010-9640-5. Epub 2010 Dec 24.
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Effect of platelet-rich plasma on dental stem cells derived from human impacted third molars.富血小板血浆对人阻生第三磨牙来源的牙髓干细胞的影响。
Regen Med. 2011 Jan;6(1):67-79. doi: 10.2217/rme.10.96.
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The effects of platelet-rich plasma derived from human umbilical cord blood on the osteogenic differentiation of human dental stem cells.人脐血来源的富血小板血浆对人牙髓干细胞成骨分化的影响。
In Vitro Cell Dev Biol Anim. 2011 Feb;47(2):157-64. doi: 10.1007/s11626-010-9364-5. Epub 2010 Nov 17.
7
Increased survival of free fat grafts with platelet-rich plasma in rabbits.富血小板血浆增加兔游离脂肪移植成活率。
J Plast Reconstr Aesthet Surg. 2010 Dec;63(12):e818-22. doi: 10.1016/j.bjps.2010.07.003. Epub 2010 Aug 13.
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Molecular basis of anti-inflammatory action of platelet-rich plasma on human chondrocytes: mechanisms of NF-κB inhibition via HGF.富血小板血浆对人软骨细胞抗炎作用的分子基础:通过 HGF 抑制 NF-κB 的机制。
J Cell Physiol. 2010 Nov;225(3):757-66. doi: 10.1002/jcp.22274.
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Platelet-rich plasma (PRP) promotes survival of fat-grafts in rats.富含血小板血浆(PRP)可促进大鼠脂肪移植的存活。
Ann Plast Surg. 2010 Jul;65(1):101-6. doi: 10.1097/SAP.0b013e3181b0273c.
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J Plast Reconstr Aesthet Surg. 2010 Nov;63(11):1769-77. doi: 10.1016/j.bjps.2009.12.002. Epub 2010 Jan 15.