Department of Otolaryngology-Head and Neck Surgery, University of Texas Medical Branch, Galveston, TX 77555, USA.
Pediatr Clin North Am. 2013 Aug;60(4):865-78. doi: 10.1016/j.pcl.2013.04.011.
Extraesophageal reflux disease, commonly called laryngopharyngeal reflux disease (LPRD), continues to be an entity with more questions than answers. Although the role of LPRD has been implicated in various pediatric diseases, it has been inadequately studied in others. LPRD is believed to contribute to failure to thrive, laryngomalacia, recurrent respiratory papillomatosis, chronic cough, hoarseness, esophagitis, and aspiration among other pathologies. Thus, LPRD should be considered as a chronic disease with a variety of presentations. High clinical suspicion along with consultation with an otolaryngologist, who can evaluate for laryngeal findings, is necessary to accurately diagnose LPRD.
食管外反流病，通常称为喉咽反流病（LPRD），仍然是一个存在更多问题而不是答案的实体。尽管 LPRD 的作用已被牵涉到各种儿科疾病中，但在其他疾病中的研究还不够充分。据信，LPRD 会导致生长发育不良、喉软化、复发性呼吸道乳头瘤病、慢性咳嗽、声音嘶哑、食管炎和吸入等病理。因此，LPRD 应被视为一种具有多种表现的慢性疾病。需要高度的临床怀疑以及咨询耳鼻喉科医生，他们可以评估喉部发现，以准确诊断 LPRD。
