Monaco W A, Wormington C M
St. Vincent's Medical Center, Jacksonville, Florida.
Optom Vis Sci. 1990 Jul;67(7):532-7. doi: 10.1097/00006324-199007000-00011.
In a survey of 100 rhesus monkeys, the prevalence of macular changes was similar to that in age-related macular degeneration in humans. Ophthalmoscopically visible drusen were observed in 31% of the monkeys. A statistically significant correlation existed between the age of the animals and the degree of drusen. Considering equivalent ages, monkeys appear to develop drusen earlier than humans. Pigment mottling occurred in 10% and hypopigmented spots in 8% of the sample. A dull foveal reflex was seen in 8% and no reflex in 27%. There was a statistically significant correlation between the absence of a reflex and the presence of pigment mottling or hypopigmentation in the macula.
在一项对100只恒河猴的调查中，黄斑变化的患病率与人类年龄相关性黄斑变性的患病率相似。在31%的猴子中观察到眼底镜可见的玻璃膜疣。动物年龄与玻璃膜疣程度之间存在统计学上的显著相关性。考虑到同等年龄，猴子似乎比人类更早出现玻璃膜疣。10%的样本出现色素斑驳，8%出现色素减退斑。8%的样本中可见中央凹反射迟钝，27%无反射。黄斑区无反射与色素斑驳或色素减退的存在之间存在统计学上的显著相关性。
