Torwane Nilesh Arjun, Hongal Sudhir, Goel Pankaj, Chandrashekar B R, Jain Manish, Saxena Eshani
Department of Public Health Dentistry, People's Dental Academy, People's University, Bhopal, Madhya Pradesh, India.
Eur J Dent. 2013 Oct;7(4):461-468. doi: 10.4103/1305-7456.120675.
The aim of this study is to evaluate the efficacy of 30% ethenolic extract of Indian propolis compared with Recaldent(™) (casein phosphopeptide-amorphous calcium phosphate) in reduction of dentinals hypersensitivity, a randomized, double-blind, split mouth, controlled clinical trial was conducted among the patients residing in Central Jail.
A sample of 73 teeth from 13 patients having at least three teeth with dentinal hypersensitivity (DH) were randomly allocated into three treatment groups: Group A: 30% ethenolic extract of Indian propolis, Group B: Recaldent(™), Group C: Sterile water. Verbal rating scale was used to record the degree of hypersensitivity based on patient's response to tactile and air blast stimuli. The baseline scores were obtained. Each intervention group received applications of their respective agents consecutively on 1(st), 7(th), 14(th), and 21(st) day. After each application the scores were recorded.
Both the 30% Indian propolis and Recaldent(™) showed significant reduction in DH.
Recaldent(™) was found to be significantly better in reducing the DH compared to propolis and sterile water (P < 0.01).
本研究旨在评估印度蜂胶30%乙醇提取物与酪蛋白磷酸肽-无定形磷酸钙（Recaldent™）相比在降低牙本质过敏症方面的疗效，在中央监狱居住的患者中进行了一项随机、双盲、双侧对照的临床试验。
从13名患者中选取73颗至少有三颗牙本质过敏（DH）牙齿的样本，随机分为三个治疗组：A组：印度蜂胶30%乙醇提取物；B组：Recaldent™；C组：无菌水。根据患者对触觉和吹气刺激的反应，使用言语评定量表记录过敏程度。获取基线分数。每个干预组在第1、7、14和21天连续接受各自药物的应用。每次应用后记录分数。
30%印度蜂胶和Recaldent™均显示出DH的显著降低。
发现Recaldent™在降低DH方面比蜂胶和无菌水显著更好（P < 0.01）。
