Liu Dong-Ze, Zhu Yi-Qun, Li Xiao-Fei, Shan Wei-Gang, Gao Peng-Fei
Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, P. R. China.
Chem Biodivers. 2014 Jun;11(6):982-6. doi: 10.1002/cbdv.201400004.
Phytochemical investigation of the AcOEt extract of G. Lucidum has led to the isolation of two new triterpenoids, 1 and 2, together with five known ones, 3-7. The structures of the new compounds were identified as 12β-acetoxy-3β,7β-dihydroxy-11,15,23-trioxolanost-8-en-26-oic acid butyl ester (1) and 12β-acetoxy-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid butyl ester (2) on the basis of detailed spectroscopic analysis (mass spectrometry, and 1D- and 2D-NMR experiments). The antimicrobial activities of 1 and 2 were also evaluated.
对灵芝乙酸乙酯提取物进行植物化学研究，已分离出两种新的三萜类化合物1和2，以及五种已知化合物3 - 7。通过详细的光谱分析（质谱以及一维和二维核磁共振实验），确定新化合物的结构分别为12β - 乙酰氧基 - 3β,7β - 二羟基 - 11,15,23 - 三氧杂羊毛甾 - 8 - 烯 - 26 - 酸丁酯（1）和12β - 乙酰氧基 - 3,7,11,15,23 - 五氧杂羊毛甾 - 8 - 烯 - 26 - 酸丁酯（2）。还评估了化合物1和2的抗菌活性。
