炎症性肠病中的替代补体途径。C3前激活物（B因子）蛋白的定量分析。
The alternate complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein.
作者信息
Feinstein P A, Kaplan S R, Thayer W R
出版信息
Gastroenterology. 1976 Feb;70(2):181-5.
A component of the complement system's alternate pathway was investigated in ulcerative colitis and Crohn's disease. The mean C3PA (Factor B) titer in normals was 74 +/- 15%; in ulcerative colitis, 92 +/- 18%; and in Crohn's disease, 119+/- 24%. Significance was at the P less than 0.001 level when the mean values for the ulcerative colitis and the Crohn's disease groups were compared to normal subjects. Titers did not change significantly with exacerbation or amelioration of the diseases or when patient groups were analyzed according to the mode of treatment received.
对补体系统替代途径的一个成分在溃疡性结肠炎和克罗恩病中进行了研究。正常人群中C3PA（B因子）的平均滴度为74±15%；溃疡性结肠炎患者中为92±18%；克罗恩病患者中为119±24%。将溃疡性结肠炎组和克罗恩病组的平均值与正常受试者相比，显著性水平为P<0.001。疾病加重或缓解时，以及根据患者接受的治疗方式对患者组进行分析时，滴度均无显著变化。
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