Erdman D D, Gary G W, Anderson L J
Division of Viral Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
J Clin Microbiol. 1989 Jun;27(6):1417-8. doi: 10.1128/jcm.27.6.1417-1418.1989.
We describe the serum immunoglobulin A (IgA) antibody response to Norwalk virus infection in human volunteers and compare it with previously described IgM and total antibody responses. Whereas specific IgA and IgM peak within 2 weeks after onset of symptoms, titers of total blocking antibody continue to rise, implying mediation by IgG antibody.
我们描述了人类志愿者感染诺如病毒后的血清免疫球蛋白A(IgA)抗体反应,并将其与先前描述的IgM和总抗体反应进行比较。虽然特异性IgA和IgM在症状出现后2周内达到峰值,但总阻断抗体的滴度持续上升,这意味着由IgG抗体介导。