Ferguson R Matthew, Khandhar Amit P, Jonasson Christian, Blomgren Jakob, Johansson Christer, Krishnan Kannan M
Department of Materials Science, University of Washington, Seattle, WA 98195 USA.
Acreo AB, SE 400 16 Göteborg, Sweden.
IEEE Trans Magn. 2013 Jul;49(7):3441-3444. doi: 10.1109/TMAG.2013.2239621.
Magnetic relaxation is exploited in innovative biomedical applications of magnetic particles such as magnetic particle imaging (MPI), magnetic fluid hyperthermia, and bio-sensing. Relaxation behavior should be optimized to achieve high performance imaging, efficient heating, and good SNR in bio-sensing. Using two AC susceptometers with overlapping frequency ranges, we have measured the relaxation behavior of a series of monodisperse magnetic particles and demonstrated that this approach is an effective way to probe particle relaxation characteristics from a few Hz to 10 MHz, the frequencies relevant for MPI, hyperthermia, and sensing.
磁弛豫被应用于磁性粒子的创新生物医学应用中，如磁粒子成像（MPI）、磁流体热疗和生物传感。应优化弛豫行为，以实现高性能成像、高效加热以及生物传感中的良好信噪比。通过使用两个频率范围重叠的交流磁化率测量仪，我们测量了一系列单分散磁性粒子的弛豫行为，并证明这种方法是探测从几赫兹到10兆赫兹（与MPI、热疗和传感相关的频率）的粒子弛豫特性的有效途径。
