Kohman Richie E, Han Xue
Department of Biomedical Engineering, Boston University, 44 Cummington Street, Boston, MA 02215, USA.
Chem Commun (Camb). 2015 Apr 4;51(26):5747-50. doi: 10.1039/c5cc00082c.
Using light irradiation as a trigger, large-scale structural reconfiguration of DNA nanostructures is demonstrated. We incorporated photo-cleavable spacers at strategic locations within the short oligonucleotide strands connecting adjacent helices within a DNA origami sphere, and then used light to transform the sphere into two tethered hemispheres.
利用光照射作为触发因素，展示了DNA纳米结构的大规模结构重构。我们在连接DNA折纸球体中相邻螺旋的短寡核苷酸链内的关键位置引入了可光裂解的间隔物，然后用光将球体转变为两个相连的半球。
