Duda Marlena, Daniels Jena, Wall Dennis P
Division of Systems Medicine, Department of Pediatrics, Stanford University, 1265 Welch Road, Stanford, CA, 94305, USA.
Department of Biomedical Data Science, Stanford University, 1265 Welch Road, Stanford, CA, 94305, USA.
J Autism Dev Disord. 2016 Jun;46(6):1953-1961. doi: 10.1007/s10803-016-2718-4.
The Mobile Autism Risk Assessment (MARA) is a new, electronically administered, 7-question autism spectrum disorder (ASD) screen to triage those at highest risk for ASD. Children 16 months-17 years (N = 222) were screened during their first visit in a developmental-behavioral pediatric clinic. MARA scores were compared to diagnosis from the clinical encounter. Participant median age was 5.8 years, 76.1 % were male, and most participants had an intelligence/developmental quotient score >85; 69 of the participants (31 %) received a clinical diagnosis of ASD. The sensitivity of the MARA in detecting ASD was 89.9 % [95 % CI = 82.7-97]; the specificity was 79.7 % [95 % CI = 73.4-86.1]. In a high-risk clinical setting, the MARA shows promise as a screen to distinguish ASD from other developmental/behavioral disorders.
移动自闭症风险评估（MARA）是一种新型的、通过电子方式管理的、包含7个问题的自闭症谱系障碍（ASD）筛查工具，用于对ASD高危人群进行分流。对年龄在16个月至17岁的儿童（N = 222）在发育行为儿科诊所首次就诊时进行了筛查。将MARA评分与临床诊断结果进行比较。参与者的年龄中位数为5.8岁，76.1%为男性，大多数参与者的智力/发育商数得分>85；69名参与者（31%）被临床诊断为ASD。MARA检测ASD的敏感性为89.9%[95%置信区间=82.7 - 97]；特异性为79.7%[95%置信区间=73.4 - 86.1]。在高危临床环境中，MARA有望作为一种筛查工具，用于区分ASD与其他发育/行为障碍。
