一种新型移动自闭症风险评估的临床评估
Clinical Evaluation of a Novel and Mobile Autism Risk Assessment.
作者信息
Duda Marlena, Daniels Jena, Wall Dennis P
机构信息
Division of Systems Medicine, Department of Pediatrics, Stanford University, 1265 Welch Road, Stanford, CA, 94305, USA.
Department of Biomedical Data Science, Stanford University, 1265 Welch Road, Stanford, CA, 94305, USA.
出版信息
J Autism Dev Disord. 2016 Jun;46(6):1953-1961. doi: 10.1007/s10803-016-2718-4.
The Mobile Autism Risk Assessment (MARA) is a new, electronically administered, 7-question autism spectrum disorder (ASD) screen to triage those at highest risk for ASD. Children 16 months-17 years (N = 222) were screened during their first visit in a developmental-behavioral pediatric clinic. MARA scores were compared to diagnosis from the clinical encounter. Participant median age was 5.8 years, 76.1 % were male, and most participants had an intelligence/developmental quotient score >85; 69 of the participants (31 %) received a clinical diagnosis of ASD. The sensitivity of the MARA in detecting ASD was 89.9 % [95 % CI = 82.7-97]; the specificity was 79.7 % [95 % CI = 73.4-86.1]. In a high-risk clinical setting, the MARA shows promise as a screen to distinguish ASD from other developmental/behavioral disorders.
移动自闭症风险评估（MARA）是一种新型的、通过电子方式管理的、包含7个问题的自闭症谱系障碍（ASD）筛查工具，用于对ASD高危人群进行分流。对年龄在16个月至17岁的儿童（N = 222）在发育行为儿科诊所首次就诊时进行了筛查。将MARA评分与临床诊断结果进行比较。参与者的年龄中位数为5.8岁，76.1%为男性，大多数参与者的智力/发育商数得分>85；69名参与者（31%）被临床诊断为ASD。MARA检测ASD的敏感性为89.9%[95%置信区间=82.7 - 97]；特异性为79.7%[95%置信区间=73.4 - 86.1]。在高危临床环境中，MARA有望作为一种筛查工具，用于区分ASD与其他发育/行为障碍。
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