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早期富含白细胞和血小板的纤维蛋白与PRGF/Endoret膜的力学性能比较。

Comparison of the Mechanical Properties of Early Leukocyte- and Platelet-Rich Fibrin versus PRGF/Endoret Membranes.

作者信息

Khorshidi Hooman, Raoofi Saeed, Bagheri Rafat, Banihashemi Hodasadat

机构信息

Department of Periodontology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of Dental Materials, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Int J Dent. 2016;2016:1849207. doi: 10.1155/2016/1849207. Epub 2016 Jan 6.

DOI:10.1155/2016/1849207
PMID:26880919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4736579/
Abstract

Objectives. The mechanical properties of membranes are important factors in the success of treatment and clinical handling. The goal of this study was to compare the mechanical properties of early leukocyte- and platelet-rich fibrin (L-PRF) versus PRGF/Endoret membrane. Materials and Methods. In this experimental study, membranes were obtained from 10 healthy male volunteers. After obtaining 20 cc venous blood from each volunteer, 10 cc was used to prepare early L-PRF (group 1) and the rest was used to get a membrane by PRGF-Endoret system (group 2). Tensile loads were applied to specimens using universal testing machine. Tensile strength, stiffness, and toughness of the two groups of membranes were calculated and compared by paired t-test. Results. The mean tensile strength and toughness were higher in group 1 with a significant difference (P < 0.05). The mean stiffness in group 1 was also higher but not statistically significant (P > 0.05). Conclusions. The results showed that early L-PRF membranes had stronger mechanical properties than membranes produced by PRGF-Endoret system. Early L-PRF membranes might have easier clinical handling and could be a more proper scaffold in periodontal regenerative procedures. The real results of the current L-PRF should be in fact much higher than what is reported here.

摘要

目的。膜的机械性能是治疗成功和临床操作的重要因素。本研究的目的是比较早期富含白细胞和血小板的纤维蛋白（L-PRF）与PRGF/Endoret膜的机械性能。材料与方法。在本实验研究中，从10名健康男性志愿者获取膜。从每位志愿者采集20 cc静脉血后，10 cc用于制备早期L-PRF（第1组），其余用于通过PRGF-Endoret系统获得膜（第2组）。使用万能试验机对标本施加拉伸载荷。通过配对t检验计算并比较两组膜的拉伸强度、刚度和韧性。结果。第1组的平均拉伸强度和韧性更高，差异有统计学意义（P < 0.05）。第1组的平均刚度也更高，但无统计学意义（P > 0.05）。结论。结果表明，早期L-PRF膜比PRGF-Endoret系统产生的膜具有更强的机械性能。早期L-PRF膜可能具有更简便的临床操作性，并且在牙周再生手术中可能是更合适的支架。目前L-PRF的实际结果实际上应该比这里报道的要高得多。

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