MMWR Morb Mortal Wkly Rep. 2016 Mar 4;65(8):211-4. doi: 10.15585/mmwr.mm6508e1.
After reports of microcephaly and other adverse pregnancy outcomes in infants of mothers infected with Zika virus during pregnancy, CDC issued a travel alert on January 15, 2016, advising pregnant women to consider postponing travel to areas with active transmission of Zika virus. On January 19, CDC released interim guidelines for U.S. health care providers caring for pregnant women with travel to an affected area, and an update was released on February 5. As of February 17, CDC had received reports of nine pregnant travelers with laboratory-confirmed Zika virus disease; 10 additional reports of Zika virus disease among pregnant women are currently under investigation. No Zika virus-related hospitalizations or deaths among pregnant women were reported. Pregnancy outcomes among the nine confirmed cases included two early pregnancy losses, two elective terminations, and three live births (two apparently healthy infants and one infant with severe microcephaly); two pregnancies (approximately 18 weeks' and 34 weeks' gestation) are continuing without known complications. Confirmed cases of Zika virus infection were reported among women who had traveled to one or more of the following nine areas with ongoing local transmission of Zika virus: American Samoa, Brazil, El Salvador, Guatemala, Haiti, Honduras, Mexico, Puerto Rico, and Samoa. This report summarizes findings from the nine women with confirmed Zika virus infection during pregnancy, including case reports for four women with various clinical outcomes. U.S. health care providers caring for pregnant women with possible Zika virus exposure during pregnancy should follow CDC guidelines for patient evaluation and management. Zika virus disease is a nationally notifiable condition. CDC has developed a voluntary registry to collect information about U.S. pregnant women with confirmed Zika virus infection and their infants. Information about the registry is in preparation and will be available on the CDC website.
在报告了孕妇感染寨卡病毒后出现小头畸形和其他不良妊娠结局后，美国疾病预防控制中心于 2016 年 1 月 15 日发布了旅行警报，建议孕妇考虑推迟前往寨卡病毒传播活跃的地区旅行。1 月 19 日，美国疾病预防控制中心发布了针对前往受影响地区旅行的孕妇的美国卫生保健提供者的临时指南，并于 2 月 5 日进行了更新。截至 2 月 17 日，美国疾病预防控制中心收到了 9 例实验室确诊的寨卡病毒病孕妇旅行者的报告；目前正在调查另外 10 例孕妇寨卡病毒病报告。没有报告孕妇寨卡病毒相关住院或死亡病例。9 例确诊病例的妊娠结局包括 2 例早期妊娠丢失、2 例选择性终止妊娠和 3 例活产（2 例明显健康婴儿和 1 例婴儿小头畸形）；2 例妊娠（约 18 周和 34 周妊娠）继续进行，无已知并发症。报告了在以下 9 个持续发生寨卡病毒本地传播的地区旅行的妇女中确诊的寨卡病毒感染病例：美属萨摩亚、巴西、萨尔瓦多、危地马拉、海地、洪都拉斯、墨西哥、波多黎各和萨摩亚。本报告总结了 9 名孕妇寨卡病毒感染确诊病例的发现结果，包括 4 名具有不同临床结局的妇女的病例报告。对可能在怀孕期间接触过寨卡病毒的孕妇进行治疗的美国卫生保健提供者应遵循美国疾病预防控制中心关于患者评估和管理的指南。寨卡病毒病是一种全国性需要报告的疾病。美国疾病预防控制中心已经开发了一个自愿登记处，以收集有关美国感染寨卡病毒的孕妇及其婴儿的信息。有关登记处的信息正在准备中，并将在疾病预防控制中心的网站上提供。
