来自红海珊瑚多指软珊瑚的卡斯巴烷二萜类化合物。
Casbane Diterpenes from Red Sea Coral Sinularia polydactyla.
作者信息
Hegazy Mohamed-Elamir F, Mohamed Tarik A, Elshamy Abdelsamed I, Al-Hammady Montaser A, Ohta Shinji, Paré Paul W
机构信息
Department of Phytochemistry, National Research Centre, El-Tahrir Street, Dokki, Giza 12622, Egypt.
Department of Natural Compound Chemistry, National Research Centre, El-Tahrir Street, Dokki, Giza 12622, Egypt.
出版信息
Molecules. 2016 Mar 3;21(3):308. doi: 10.3390/molecules21030308.
The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4-5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis.
软珊瑚属的Sinularia是生物活性代谢产物的丰富来源，其含有各种各样的化学结构。多指软珊瑚（Sinularia polydactyla）的溶剂提取物导致分离出三种新的卡斯巴烷二萜：多指软珊瑚卡斯巴烷M（1）、多指软珊瑚卡斯巴烷N（2）和多指软珊瑚卡斯巴烷O（3）；此外，还分离出了已知的代谢产物（4 - 5）。通过光谱分析阐明了这些化合物；通过X射线分析确定了绝对构型。
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