Le Trong-Ngoc, Bao Pham The, Huynh Hieu Trung
Faculty of Information Technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao, Go Vap District, Ho Chi Minh City, Vietnam; Faculty of Information Technology, University of Science, 227 Nguyen Van Cu, District 5, Ho Chi Minh City, Vietnam.
Faculty of Mathematics and Computer Science, University of Science, 227 Nguyen Van Cu, District 5, Ho Chi Minh City, Vietnam.
Biomed Res Int. 2016;2016:3219068. doi: 10.1155/2016/3219068. Epub 2016 Aug 14.
Objective. Our objective is to develop a computerized scheme for liver tumor segmentation in MR images. Materials and Methods. Our proposed scheme consists of four main stages. Firstly, the region of interest (ROI) image which contains the liver tumor region in the T1-weighted MR image series was extracted by using seed points. The noise in this ROI image was reduced and the boundaries were enhanced. A 3D fast marching algorithm was applied to generate the initial labeled regions which are considered as teacher regions. A single hidden layer feedforward neural network (SLFN), which was trained by a noniterative algorithm, was employed to classify the unlabeled voxels. Finally, the postprocessing stage was applied to extract and refine the liver tumor boundaries. The liver tumors determined by our scheme were compared with those manually traced by a radiologist, used as the "ground truth." Results. The study was evaluated on two datasets of 25 tumors from 16 patients. The proposed scheme obtained the mean volumetric overlap error of 27.43% and the mean percentage volume error of 15.73%. The mean of the average surface distance, the root mean square surface distance, and the maximal surface distance were 0.58 mm, 1.20 mm, and 6.29 mm, respectively.
目的。我们的目标是开发一种用于磁共振图像中肝脏肿瘤分割的计算机化方案。材料与方法。我们提出的方案包括四个主要阶段。首先,通过使用种子点提取T1加权磁共振图像系列中包含肝脏肿瘤区域的感兴趣区域(ROI)图像。对该ROI图像中的噪声进行了降低,并增强了边界。应用三维快速行进算法生成被视为教师区域的初始标记区域。使用通过非迭代算法训练的单隐藏层前馈神经网络(SLFN)对未标记的体素进行分类。最后,应用后处理阶段来提取和细化肝脏肿瘤边界。将我们的方案确定的肝脏肿瘤与放射科医生手动描绘的肿瘤进行比较,后者用作“真实情况”。结果。该研究在来自16名患者的25个肿瘤的两个数据集上进行了评估。所提出的方案获得的平均体积重叠误差为27.43%,平均体积百分比误差为15.73%。平均表面距离、均方根表面距离和最大表面距离的平均值分别为0.58毫米、1.20毫米和6.29毫米。
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