Huhn D, Meister P
Cancer. 1978 Sep;42(3):1341-9. doi: 10.1002/1097-0142(197809)42:3<1341::aid-cncr2820420345>3.0.co;2-s.
The clinical, morphologic, and cytochemical findings of 7 patients with malignant histiocytosis are presented in this study. The diagnoses were confirmed by the use of electron microscopy and cytochemistry (acid phosphatase and naphthol-AS-acetate-esterase). Two different types of malignant histiocytes were identified by the differentiation and development of cell organells. The relation of malignant histiocytosis to monocytic leukemia and to normal histiocytes (and their precursors) is discussed. And finally, there are statements on the origin and peculiarities of malignant histiocytes.
本研究报告了7例恶性组织细胞增多症患者的临床、形态学及细胞化学检查结果。诊断经电子显微镜及细胞化学方法（酸性磷酸酶和萘酚 - AS - 醋酸酯酶）得以证实。通过细胞器的分化和发育，鉴定出两种不同类型的恶性组织细胞。文中讨论了恶性组织细胞增多症与单核细胞白血病以及正常组织细胞（及其前体）的关系。最后，阐述了恶性组织细胞的起源及特点。
