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新型口服β-内酰胺类药物和大环内酯类药物对幽门螺杆菌的体外活性

In vitro activities of new oral beta-lactams and macrolides against Campylobacter pylori.

作者信息

García-Rodríguez J A, García Sánchez J E, García García M I, García Sánchez E, Muñoz Bellido J L

机构信息

Department of Microbiology, Hospital Clínico Universitario, Salamanca, Spain.

出版信息

Antimicrob Agents Chemother. 1989 Sep;33(9):1650-1. doi: 10.1128/AAC.33.9.1650.

Abstract

The in vitro activities of amoxicillin, cefuroxime, ceftetrame, cefetamet, cefixime, tigemonam, erythromycin, roxithromycin, and dirithromycin against 30 clinical isolates of Campylobacter pylori were determined by an agar dilution technique. Roxithromycin and amoxicillin (MICs for 90% of isolates tested, 0.01 and 0.06 micrograms/ml, respectively) were the most active antibiotics tested, but all strains were susceptible to all antimicrobial agents tested.

摘要

采用琼脂稀释法测定了阿莫西林、头孢呋辛、头孢替安、头孢他美、头孢克肟、替莫南、红霉素、罗红霉素和地红霉素对30株幽门螺杆菌临床分离株的体外活性。罗红霉素和阿莫西林(分别对90%受试分离株的MIC为0.01和0.06微克/毫升)是受试活性最强的抗生素,但所有菌株对所有受试抗菌药物均敏感。

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