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新型口服β-内酰胺类药物和大环内酯类药物对幽门螺杆菌的体外活性

In vitro activities of new oral beta-lactams and macrolides against Campylobacter pylori.

作者信息

García-Rodríguez J A, García Sánchez J E, García García M I, García Sánchez E, Muñoz Bellido J L

机构信息

Department of Microbiology, Hospital Clínico Universitario, Salamanca, Spain.

出版信息

Antimicrob Agents Chemother. 1989 Sep;33(9):1650-1. doi: 10.1128/AAC.33.9.1650.

DOI:10.1128/AAC.33.9.1650
PMID:2817868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC172726/
Abstract

The in vitro activities of amoxicillin, cefuroxime, ceftetrame, cefetamet, cefixime, tigemonam, erythromycin, roxithromycin, and dirithromycin against 30 clinical isolates of Campylobacter pylori were determined by an agar dilution technique. Roxithromycin and amoxicillin (MICs for 90% of isolates tested, 0.01 and 0.06 micrograms/ml, respectively) were the most active antibiotics tested, but all strains were susceptible to all antimicrobial agents tested.

摘要

采用琼脂稀释法测定了阿莫西林、头孢呋辛、头孢替安、头孢他美、头孢克肟、替莫南、红霉素、罗红霉素和地红霉素对30株幽门螺杆菌临床分离株的体外活性。罗红霉素和阿莫西林（分别对90%受试分离株的MIC为0.01和0.06微克/毫升）是受试活性最强的抗生素，但所有菌株对所有受试抗菌药物均敏感。

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本文引用的文献

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Spiral organisms in endoscopic biopsies of the human stomach.人胃内镜活检中的螺旋状生物体。
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Comparative in vitro activity and beta-lactamase stability of FR 17027, a new orally active cephalosporin.新型口服活性头孢菌素FR 17027的体外活性及β-内酰胺酶稳定性比较
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Unidentified curved bacilli on gastric epithelium in active chronic gastritis.活动性慢性胃炎胃上皮中未鉴定出的弯曲杆菌。
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Relation of Campylobacter pyloridis to gastritis and peptic ulcer.幽门弯曲菌与胃炎及消化性溃疡的关系。
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Susceptibility of Campylobacter pyloridis to three macrolide antibiotics (erythromycin, roxithromycin [RU 28965], and CP 62,993) and rifampin.幽门弯曲菌对三种大环内酯类抗生素（红霉素、罗红霉素[RU 28965]和CP 62993）及利福平的敏感性。
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The minimum inhibitory and bactericidal concentrations of antibiotics and anti-ulcer agents against Campylobacter pyloridis.抗生素和抗溃疡药物对幽门弯曲菌的最低抑菌浓度和杀菌浓度。
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