评估光学相干断层扫描系统灵敏度的方法。
Methods to assess sensitivity of optical coherence tomography systems.
作者信息
Agrawal Anant, Pfefer T Joshua, Woolliams Peter D, Tomlins Peter H, Nehmetallah George
机构信息
Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD, USA.
Functional Materials Group, National Physical Laboratory, Teddington, UK.
出版信息
Biomed Opt Express. 2017 Jan 18;8(2):902-917. doi: 10.1364/BOE.8.000902. eCollection 2017 Feb 1.
Abstract
Measuring the sensitivity of an optical coherence tomography (OCT) system determines the minimum sample reflectivity it can detect and provides a figure of merit for system optimization and comparison. The published literature lacks a detailed description of OCT sensitivity measurement procedures. Here we describe a commonly-used measurement method and introduce two new phantom-based methods, which also offer a means to directly visualize low reflectivity conditions relevant to biological tissue. We provide quantitative results for the three methods from different OCT system configurations and discuss the methods' advantages and disadvantages.
摘要
测量光学相干断层扫描（OCT）系统的灵敏度可确定其能够检测到的最小样本反射率，并为系统优化和比较提供一个品质因数。已发表的文献中缺乏对OCT灵敏度测量程序的详细描述。在此，我们描述一种常用的测量方法，并介绍两种基于体模的新方法，这两种方法还提供了一种直接可视化与生物组织相关的低反射率情况的手段。我们给出了来自不同OCT系统配置的这三种方法的定量结果，并讨论了这些方法的优缺点。
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