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使用自体牙移植与β-磷酸三钙异体材料进行牙槽嵴保存:一项随机、对照、前瞻性临床试点研究。

Alveolar ridge preservation using autogenous tooth graft versus beta-tricalcium phosphate alloplast: A randomized, controlled, prospective, clinical pilot study.

作者信息

Joshi Chaitanya Pradeep, Dani Nitin Hemchandra, Khedkar Smita Uday

机构信息

Department of Periodontics, MGV's KBH Dental College and Hospital, Nashik, Maharashtra, India.

Department of Microbiology, MGV's KBH Dental College and Hospital, Nashik, Maharashtra, India.

出版信息

J Indian Soc Periodontol. 2016 Jul-Aug;20(4):429-434. doi: 10.4103/0972-124X.188335.

Abstract

BACKGROUND

A randomized, prospective clinical, radiographical, and histological study was conducted to evaluate healing after alveolar ridge preservation technique using two different graft materials, namely, a novel autogenous graft material i. e., autogenous tooth graft (ATG) and beta-tricalcium phosphate (β-TCP) alloplast.

MATERIALS AND METHODS

Fifteen patients undergoing extraction of at least three teeth were selected. Atraumatic extractions were performed. Of the three extraction sockets, one was grafted with ATG, other with β-TCP, and the third was left ungrafted. Cone-beam computed tomography scans were taken immediately after grafting and 4 months postoperatively to check the changes in alveolar crest height and width at all the sites. Three patients in whom implant placement was done after complete healing; bone samples were harvested using a 3 mm diameter trephine during osteotomy preparation from both the ridge preserved sites and studied histologically.

RESULTS

There was a statistically significant difference when the changes in width and height of alveolar crest were compared within all the three groups ( < 0.05). Among three sites, ATG-grafted sites showed the most superior results with a minimal reduction in alveolar crest height and width. Histological analysis also showed the same trend with more new bone formation at ATG-grafted sites as compared to β-TCP-grafted sites.

CONCLUSION

Postextraction, ridge preservation leads to more predictable maintenance of alveolar ridge height and width. ATG as compared to β-TCP provided superior results. Based on this, we conclude that ATG material can serve as a better alternative to conventional bone graft materials.

摘要

背景

进行了一项随机、前瞻性临床、影像学和组织学研究,以评估使用两种不同移植材料(即新型自体移植材料,即自体牙移植(ATG)和β-磷酸三钙(β-TCP)异体材料)进行牙槽嵴保存技术后的愈合情况。

材料与方法

选择15例至少拔除三颗牙齿的患者。进行无创拔牙。在三个拔牙窝中,一个用ATG移植,另一个用β-TCP移植,第三个不进行移植。移植后立即和术后4个月进行锥形束计算机断层扫描,以检查所有部位牙槽嵴高度和宽度的变化。在完全愈合后进行种植体植入的三名患者;在截骨准备过程中,使用3毫米直径的环钻从两个保存牙槽嵴的部位采集骨样本,并进行组织学研究。

结果

在所有三组中比较牙槽嵴宽度和高度的变化时,存在统计学上的显著差异(<0.05)。在三个部位中,ATG移植部位显示出最优异的结果,牙槽嵴高度和宽度的减少最小。组织学分析也显示出相同的趋势,与β-TCP移植部位相比,ATG移植部位有更多的新骨形成。

结论

拔牙后,牙槽嵴保存可更可预测地维持牙槽嵴的高度和宽度。与β-TCP相比,ATG提供了更优异的结果。基于此,我们得出结论,ATG材料可作为传统骨移植材料的更好替代品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dafd/5341319/8ae222348a6f/JISP-20-429-g001.jpg

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