Mohebitabar Safieh, Shirazi Mahboobeh, Bioos Sodabeh, Rahimi Roja, Malekshahi Farhad, Nejatbakhsh Fatemeh
Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Maternal, Fetal, and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Avicenna J Phytomed. 2017 May-Jun;7(3):206-213.
Rose oil is obtained from the petals of difference Rosa species especially L. and Mill. Various pharmacological properties have been attributed to rose oil. The aim of the present study was to review the rose oil therapeutic effects which had been clinically evaluated in trial studies.
Google scholar, PubMed, Cochrane Library, and Scopus were searched for human studies which have evaluated the therapeutic effects of rose oil and published in English language until August 2015.
Thirteen clinical trials (772 participants) were included in this review. Rose oil was administered via inhalation or used topically. Most of the studies (five trials) evaluated the analgesic effect of rose oil. Five studies evaluated the physiological relaxation effect of rose oil. Anti-depressant, psychological relaxation, improving sexual dysfunction, and anti-anxiety effects were the other clinical properties reported for rose oil.
Numerous studies on the pharmacological properties of rose oil have been done in animals, but studies in humans are few. In this study, it was observed that rose oil had physiological and psychological relaxation, analgesic and anti-anxiety effects. To obtain conclusive results on the efficacy and safety of rose oil, further clinical trials with larger sample size and better designation are required.
玫瑰油是从不同蔷薇属物种尤其是百叶蔷薇和法国蔷薇的花瓣中提取的。玫瑰油具有多种药理特性。本研究的目的是综述在试验研究中经过临床评估的玫瑰油的治疗效果。
检索谷歌学术、PubMed、考克兰图书馆和Scopus数据库，查找截至2015年8月已发表的评估玫瑰油治疗效果的英文人体研究。
本综述纳入了13项临床试验（772名参与者）。玫瑰油通过吸入或局部使用。大多数研究（五项试验）评估了玫瑰油的镇痛效果。五项研究评估了玫瑰油的生理放松效果。玫瑰油还具有抗抑郁、心理放松、改善性功能和抗焦虑等其他临床特性。
关于玫瑰药理特性的研究在动物身上已进行了很多，但人体研究较少。在本研究中，观察到玫瑰油具有生理和心理放松、镇痛和抗焦虑作用。为了获得关于玫瑰油疗效和安全性的确切结果，需要进行样本量更大、设计更优的进一步临床试验。
