Perán Macarena, García María Angel, Lopez-Ruiz Elena, Jiménez Gema, Marchal Juan Antonio
Department of Health Sciences, University of Jaén, Campus Las Lagunillas, S/N, Jaén 23071, Spain.
Research Unit, University Hospital "Virgen de las Nieves", Avda. de las Fuerzas Armadas, 2, Granada 18014, Spain.
Materials (Basel). 2013 Mar 28;6(4):1333-1359. doi: 10.3390/ma6041333.
Nanotechnologists have become involved in regenerative medicine creation of biomaterials and nanostructures with potential clinical implications. Their aim is to develop systems that can mimic, reinforce or even create tissue repair strategies. In fact, in the last decade, important advances in the field of tissue engineering, cell therapy and cell delivery have already been achieved. In this review, we will delve into the latest research advances and discuss whether cell and/or tissue repair devices are a possibility. Focusing on the application of nanotechnology in tissue engineering research, this review highlights recent advances in the application of nano-engineered scaffolds designed to replace or restore the followed tissues: (i) skin; (ii) cartilage; (iii) bone; (iv) nerve; and (v) cardiac.
纳米技术专家已参与到再生医学领域，致力于创造具有潜在临床意义的生物材料和纳米结构。他们的目标是开发能够模拟、强化甚至创造组织修复策略的系统。事实上，在过去十年中，组织工程、细胞治疗和细胞递送领域已经取得了重要进展。在本综述中，我们将深入探讨最新的研究进展，并讨论细胞和/或组织修复装置是否可行。本综述聚焦于纳米技术在组织工程研究中的应用，重点介绍了纳米工程支架在以下组织替代或修复方面的最新应用进展：（i）皮肤；（ii）软骨；（iii）骨；（iv）神经；以及（v）心脏。
