Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, 81744-176, Iran.
Department of Immunology, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
Med Oncol. 2017 Sep 27;34(11):183. doi: 10.1007/s12032-017-1044-9.
Probiotics and fermented milk products have attracted the attention of scientists from various fields, such as health care, industry and pharmacy. In recent years, reports have shown that dietary probiotics such as kefir have a great potential for cancer prevention and treatment. Kefir is fermented milk with Caucasian and Tibet origin, made from the incubation of kefir grains with raw milk or water. Kefir grains are a mixture of yeast and bacteria, living in a symbiotic association. Antibacterial, antifungal, anti-allergic and anti-inflammatory effects are some of the health beneficial properties of kefir grains. Furthermore, it is suggested that some of the bioactive compounds of kefir such as polysaccharides and peptides have great potential for inhibition of proliferation and induction of apoptosis in tumor cells. Many studies revealed that kefir acts on different cancers such as colorectal cancer, malignant T lymphocytes, breast cancer and lung carcinoma. In this review, we have focused on anticancer properties of kefir.
益生菌和发酵乳产品引起了来自保健、工业和制药等各个领域的科学家的关注。近年来,有报道称,开菲尔等膳食益生菌在癌症预防和治疗方面具有巨大潜力。开菲尔是源自高加索和西藏的发酵乳,由开菲尔粒与生乳或水混合发酵而成。开菲尔粒是酵母和细菌的混合物,以共生的方式存在。开菲尔粒具有抗菌、抗真菌、抗过敏和抗炎作用等有益健康的特性。此外,有人认为开菲尔中的一些生物活性化合物,如多糖和肽,具有抑制肿瘤细胞增殖和诱导细胞凋亡的巨大潜力。许多研究表明,开菲尔对结直肠癌、恶性 T 淋巴细胞、乳腺癌和肺癌等多种癌症都有作用。在这篇综述中,我们重点介绍了开菲尔的抗癌特性。