ComplexViewer：已编辑的大分子复合物的可视化工具。
ComplexViewer: visualization of curated macromolecular complexes.
机构信息
Wellcome Trust Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9?3BF, UK.
European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Genome Campus, CB10?1SD, Cambridge, UK.
出版信息
Bioinformatics. 2017 Nov 15;33(22):3673-3675. doi: 10.1093/bioinformatics/btx497.
SUMMARY
Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex.
AVAILABILITY AND IMPLEMENTATION
freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js.
CONTACT
摘要
蛋白质通常作为复合物、多种蛋白质和其他生物分子的集合的一部分发挥作用，但网络可视化通常仅将蛋白质显示为二进制相互作用的一部分。ComplexViewer 可视化具有两个以上参与者的相互作用，从而避免了首先将这些相互作用扩展为多个二进制相互作用的需要。此外，如果已知分子之间的结合区域，则可以在更大的复合物上下文中显示这些区域。
可用性和实现
根据 Apache 版本 2 许可证免费提供；EMBL-EBI 复合物门户：http://www.ebi.ac.uk/complexportal；源代码：https://github.com/MICommunity/ComplexViewer；包：https://www.npmjs.com/package/complexviewer；http://biojs.io/d/complexviewer。语言：JavaScript；Web 技术：可伸缩矢量图形；库：D3.js。
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