Candotto V, Lauritano D, Nardone M, Baggi L, Arcuri C, Gatto R, Gaudio R M, Spadari F, Carinci F
Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy.
Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.
Oral Implantol (Rome). 2017 Nov 30;10(3):209-220. doi: 10.11138/orl/2017.10.3.209. eCollection 2017 Jul-Sep.
The aim of this paper is to describe epidemiology and clinical manifestations of oral infection by Human papillomavirus (HPV), with particular attention to potential malignant lesions.
A systematic review of the literature was conducted to describe the state of the art about HPV infection in oropharyngeal mucosa and its modalities of transmission, with particular attention to possible simultaneous infection in multiple anatomic sites. The aspects of prevention and control of infection by administering vaccines and the diffusion of sexual education campaigns are discussed also. Therapeutic protocols are also described where necessary.
In recent years there has been a growing interest in HPV oral medicine, suggesting a role of such a family of viruses in the development of neoplasms of the oropharyngeal district as well as of the uterine cervix. Even if the mass media have increasingly faced the problem, causing frequent alarming among patients, the dentist therefore needs a complete and up-to-date knowledge of this infectious condition that is one of the most common causes of sexually transmitted mucous membrane infections (e.g. genital, anal and oral).
Recent studies about HPV infection are a basic requirement in order to promote the health of patients and provide them with the most exhaustive indications from dentists.
本文旨在描述人乳头瘤病毒（HPV）口腔感染的流行病学和临床表现，尤其关注潜在的恶性病变。
对文献进行系统综述，以描述口咽黏膜HPV感染的现状及其传播方式，特别关注多个解剖部位可能同时发生的感染。还讨论了通过接种疫苗预防和控制感染的方面以及性教育活动的普及情况。必要时也描述了治疗方案。
近年来，人们对HPV口腔医学的兴趣日益浓厚，这表明这类病毒在口咽区以及子宫颈肿瘤的发生发展中起作用。即使大众媒体越来越多地关注这个问题，导致患者频繁恐慌，但牙医仍需要全面、最新地了解这种感染状况，它是性传播黏膜感染（如生殖器、肛门和口腔感染）最常见的原因之一。
近期关于HPV感染的研究是促进患者健康并为他们提供牙医最详尽建议的基本要求。
