培养基和方法对铜绿假单胞菌及其他细菌体外对环丙沙星和依诺沙星敏感性的影响。
Influence of medium and method on the in vitro susceptibility of Pseudomonas aeruginosa and other bacteria to ciprofloxacin and enoxacin.
作者信息
Blaser J, Dudley M N, Gilbert D, Zinner S H
出版信息
Antimicrob Agents Chemother. 1986 May;29(5):927-9. doi: 10.1128/AAC.29.5.927.
Abstract
Ciprofloxacin and enoxacin were two- to fourfold less active against Pseudomonas aeruginosa in calcium- and magnesium-supplemented broth compared with unsupplemented broth regardless of inoculum size, presence of serum, or use of inhibitory or bactericidal endpoints (P less than 0.01). The effect of cation supplementation was less pronounced and less consistent for Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus.
摘要
在添加钙和镁的肉汤中，环丙沙星和依诺沙星对铜绿假单胞菌的活性比未添加的肉汤低两到四倍，无论接种量大小、血清的存在与否，或使用抑菌或杀菌终点（P小于0.01）。对于大肠杆菌、肺炎克雷伯菌和金黄色葡萄球菌，阳离子补充的影响不那么明显且不太一致。
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