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使用新型15毫米直径治疗光束的脉冲染料激光治疗酒渣鼻。

Pulsed dye laser treatment of rosacea using a novel 15 mm diameter treatment beam.

作者信息

Bernstein Eric F, Schomacker Kevin, Paranjape Amit, Jones Christopher J

机构信息

Mainline Center for Laser Surgery, Ardmore, Pennsylvania.

Syneron-Candela Corporation, Wayland, Massachusetts.

出版信息

Lasers Surg Med. 2018 Oct;50(8):808-812. doi: 10.1002/lsm.22819. Epub 2018 Apr 10.

Abstract

BACKGROUND

The pulsed-dye laser has been used to treat facial redness and rosacea for decades. Recent advances in dye laser technology enable 50% higher output energies supporting 50% larger treatment areas, and beam-diameters up to 15 mm with clinically-relevant fluences. In this study, we investigate this novel pulsed-dye laser using a 15 mm diameter beam for treatment of rosacea.

METHODS

Twenty subjects with erythemato-telangiectatic rosacea were enrolled in the study. A total of 4 monthly treatments were administered, first treating linear vessels with a 3 × 10 mm elliptical beam, then diffuse redness with a 15-mm diameter circular beam. Blinded assessment of digital, cross-polarized photographs taken 2 months following the last treatment was performed using an 11-point clearance scale.

RESULTS

Nineteen subjects completed the study. Blinded reviewers correctly identified baseline photos in 55 out of the total of 57 images (96.5%). The blinded reviewers scored 17 of the 19 subjects with an improvement greater than 40%, and 11 of the 19 subjects greater than 50%. The average improvement was 53.9%. Side effects were limited to mild edema, mild to moderate erythema, and mild to moderate bruising.

CONCLUSION

This study demonstrates that a newly designed pulsed-dye laser having a novel 15-mm diameter treatment beam improves the appearance of rosacea with a favorable safety profile. Lasers Surg. Med. 50:808-812, 2018. © 2018 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.

摘要

背景

脉冲染料激光用于治疗面部红斑和酒渣鼻已有数十年历史。染料激光技术的最新进展使输出能量提高了50%,可支持的治疗面积增大了50%,且光束直径可达15毫米,具有临床相关的能量密度。在本研究中,我们使用直径为15毫米的光束的新型脉冲染料激光来治疗酒渣鼻。

方法

20名患有红斑毛细血管扩张型酒渣鼻的受试者参与了本研究。共进行了4次每月一次的治疗,首先用3×10毫米的椭圆形光束治疗线性血管,然后用直径为15毫米的圆形光束治疗弥漫性红斑。在最后一次治疗后2个月拍摄数字交叉偏振照片,并使用11分清除量表进行盲法评估。

结果

19名受试者完成了研究。盲法评估者在总共57张图像中的55张(96.5%)中正确识别出了基线照片。盲法评估者对19名受试者中的17名评分显示改善超过40%,对19名受试者中的11名评分显示改善超过50%。平均改善率为53.9%。副作用仅限于轻度水肿、轻度至中度红斑和轻度至中度瘀伤。

结论

本研究表明,一种新设计的具有新型15毫米直径治疗光束的脉冲染料激光可改善酒渣鼻外观,且安全性良好。《激光外科与医学》50:808 - 812,2018年。©2018作者。《激光在外科与医学中的应用》由威利期刊公司出版。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b164/6175346/a6f8f11621dc/LSM-50-808-g001.jpg

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