趋生态性：原理及其在霍奇金病研究中的应用
Ecotaxis: the principle and its application to the study of Hodgkin's disease.
作者信息
Sousa M D, Yang M, Lopes-Corrales E, Tan C, Hansen J A, Dupont B, Good R A
出版信息
Clin Exp Immunol. 1977 Jan;27(1):143-51.
Abstract
A study of the function, characterization and distribution of T and B lymphocytes in five children with Hodgkin's disease is presented. The results, indicating that lymphocyte depletion in the peripheral blood does not necessarily reflect an overall lack of circulating lymphocytes, are presented to demonstrate that failure of ecotaxis (normal lymphocyte migration and distribution) can occur in man. The underlying reasons for such failure and their relevance to the pathogenesis of Hodgkin's disease are discussed.
摘要
本文介绍了对五名霍奇金病患儿T和B淋巴细胞的功能、特征及分布的研究。结果表明外周血淋巴细胞减少并不一定反映循环淋巴细胞的总体缺乏，旨在证明人类可能发生趋化性障碍（正常淋巴细胞迁移和分布）。文中讨论了这种障碍的潜在原因及其与霍奇金病发病机制的相关性。
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Ecotaxis: the principle and its application to the study of Hodgkin's disease.趋生态性：原理及其在霍奇金病研究中的应用
Clin Exp Immunol. 1977 Jan;27(1):143-51.
2
[Proportions and absolute count of T- and B-lymphocytes in peripheral blood and their blastic transformation induced by mitogens in splenectomized and non-splenectomized patients with Hodgkin's disease].[霍奇金病脾切除和未脾切除患者外周血中T淋巴细胞和B淋巴细胞的比例及绝对计数，以及丝裂原诱导的其母细胞转化]
Acta Haematol Pol. 1978 Jan-Mar;9(1):37-44.
3
Immunologic parameters in childhood Hodgkin's disease II. T and B lymphocytes in the peripheral blood of normal children and in the spleen and peripheral blood of children with Hodgkin's disease.儿童霍奇金病的免疫学参数II. 正常儿童外周血以及霍奇金病患儿脾脏和外周血中的T和B淋巴细胞
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SPLEEN/PATHOL.脾脏/病理学
Am J Clin Pathol. 1976 Jan;65(1):30-9.
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Spleen lymphocyte populations in patients with Hodgkin's disease--properties of cells with different densities.霍奇金病患者的脾脏淋巴细胞群体——不同密度细胞的特性
Clin Exp Immunol. 1982 May;48(2):300-6.
8
Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes.霍奇金病中淋巴细胞转化受损。循环T淋巴细胞耗竭的证据。
J Clin Invest. 1973 Aug;52(8):1908-17. doi: 10.1172/JCI107374.
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Hodgkin's disease in children: investigation of T and B lymphocytes.儿童霍奇金病：T和B淋巴细胞的研究
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引用本文的文献
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Human lymphocyte traffic assessed by indium-111 oxine labelling: clinical observations.通过铟-111 氧肟酸标记评估人类淋巴细胞转运：临床观察
Clin Exp Immunol. 1981 Mar;43(3):443-9.
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Natural killer (NK) activity in the spleen of patients with Hodgkin's disease and controls.霍奇金病患者与对照组脾脏中的自然杀伤（NK）活性。
Br J Cancer. 1982 Nov;46(5):806-10. doi: 10.1038/bjc.1982.274.
3
Spleen lymphocyte populations in patients with Hodgkin's disease--properties of cells with different densities.霍奇金病患者的脾脏淋巴细胞群体——不同密度细胞的特性
Clin Exp Immunol. 1982 May;48(2):300-6.
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Distribution of T-lymphocyte subsets in Hodgkin's disease characterized by monoclonal antibodies.以单克隆抗体为特征的霍奇金病中T淋巴细胞亚群的分布
Br J Cancer. 1982 Apr;45(4):491-9. doi: 10.1038/bjc.1982.84.
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Defective in vitro antibody production to Varicella zoster and other virus antigens in patients with Hodgkin's disease.霍奇金病患者对水痘带状疱疹及其他病毒抗原的体外抗体产生存在缺陷。
Clin Exp Immunol. 1983 Aug;53(2):297-307.
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Spontaneous and Concanavalin A-induced suppressor activity in control and Hodgkin's disease patients.对照患者和霍奇金病患者的自发及伴刀豆球蛋白A诱导的抑制活性
Br J Cancer. 1984 Mar;49(3):349-56. doi: 10.1038/bjc.1984.55.
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Subsets of blood, spleen and recirculating lymphocytes in man.人类血液、脾脏和再循环淋巴细胞的亚群。
Clin Exp Immunol. 1983 Sep;53(3):672-8.
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Evaluation of the circulating and splenic lymphocyte subpopulations in patients with non-Hodgkin lymphomas and Hodgkin's disease using monoclonal antibodies.使用单克隆抗体对非霍奇金淋巴瘤和霍奇金病患者循环及脾脏淋巴细胞亚群的评估。
Blut. 1983 Jul;47(1):41-51. doi: 10.1007/BF00321049.
本文引用的文献
1
The recirculation of lymphocytes from blood to lymph in the rat.大鼠体内淋巴细胞从血液到淋巴的再循环。
J Physiol. 1959 Apr 23;146(1):54-69. doi: 10.1113/jphysiol.1959.sp006177.
2
Thymus-dependent and thymus-independent populations: origin, migratory patterns and lifespan.胸腺依赖和非胸腺依赖群体：起源、迁移模式和寿命。
Clin Exp Immunol. 1971 May;8(5):663-84.
3
Kinetics of the distribution of thymus and marrow cells in the peripheral lymphoid organs of the mouse: ecotaxis.小鼠外周淋巴器官中胸腺和骨髓细胞的分布动力学：生态趋向性。
Clin Exp Immunol. 1971 Sep;9(3):371-80.
4
The traffic of lymphocytes.淋巴细胞的运输
Semin Hematol. 1969 Jan;6(1):67-83.
5
Recent immunological findins in Hodgkin's disease.霍奇金淋巴瘤的近期免疫学研究发现
Tumori. 1973 Sep-Oct;59(5):363-73. doi: 10.1177/030089167305900508.
6
Impaired delayed-hypersensitivity responses in 154 patients with untreated Hodgkin's disease.154例未经治疗的霍奇金病患者的迟发型超敏反应受损。
Natl Cancer Inst Monogr. 1973 May;36:107-15.
7
Depletion of thymus dependent lymphocytes in Hodgkin's disease.霍奇金病中胸腺依赖淋巴细胞的耗竭。
Scand J Haematol. 1974;12(4):263-9. doi: 10.1111/j.1600-0609.1974.tb00208.x.
8
Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes.霍奇金病中淋巴细胞转化受损。循环T淋巴细胞耗竭的证据。
J Clin Invest. 1973 Aug;52(8):1908-17. doi: 10.1172/JCI107374.
9
10
Impaired lymphocyte function in untreated Hodgkin's disease.未经治疗的霍奇金淋巴瘤患者淋巴细胞功能受损。
N Engl J Med. 1974 Jan 24;290(4):181-6. doi: 10.1056/NEJM197401242900402.
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