Xing Fei, Liu Guoming, Duan Xin, Xiang Zhou
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.
Department of Orthopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041,
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2018 Nov 15;32(11):1477-1482. doi: 10.7507/1002-1892.201804024.
To review the application of urine derived stem cells (USCs) in regeneration of musculoskeletal system.
The original literature about USCs in the regeneration of musculoskeletal system was extensively reviewed and analyzed.
The source of USCs is noninvasive and extensive. USCs express MSCs surface markers with stable proliferative and multi-directional differentiation capabilities, and are widely used in bone, skin, nerve, and other skeletal and muscle system regeneration fields and show a certain repair capacity.
USCs from non-invasive sources have a wide application prospect in the regeneration of musculoskeletal system, but the definite biological mechanism of its repair needs further study.
综述尿液来源干细胞（USCs）在肌肉骨骼系统再生中的应用。
广泛回顾并分析了关于USCs在肌肉骨骼系统再生方面的原始文献。
USCs的来源具有非侵入性且广泛。USCs表达间充质干细胞表面标志物，具有稳定的增殖和多向分化能力，被广泛应用于骨、皮肤、神经等骨骼肌肉系统再生领域，并显示出一定的修复能力。
非侵入性来源的USCs在肌肉骨骼系统再生中具有广阔的应用前景，但其修复的确切生物学机制有待进一步研究。
