Biomedical Optics Laboratory, Department of Applied Physics, Indian Institute of Technology (Indian School of Mines), Dhanbad, Jharkhand, 826004, India.
Lasers Med Sci. 2019 Aug;34(6):1167-1176. doi: 10.1007/s10103-018-02706-z. Epub 2019 Jan 8.
In the proposed work, we report on qualitative as well as quantitative biospeckle monitoring of functional blood flow on the human hand. Intensity-based algorithms namely generalized difference and our earlier proposed algorithm parameterized global-average Fujii have been approached for the first time to analyze various physiological changes due to effect of different treatments such as hot and cold water treatments on the palm which can be helpful in examining cardiovascular and related diseases. In addition, blood flow has been monitored for the first time on face scrub, beauty creams, and pain relief ointments applied over the back of the palm. It has been found that, on application of four beauty creams namely Fair & Lovely, Ponds White Beauty, Vicco Turmeric, and Lotus Herbals Safe Sun on the back of the palm, blood flow increases and becomes highest (mean activity, 154.87) for Fair & Lovely among the four beauty creams. In addition, pain relief ointments such as Volini, Fast Relief, Molid Gel, and Zandu Gel increase blood flow after their applications on the back of the palm and Volini gives maximum increase of average blood flow (31.59) and hence can be considered one of the best among the four ointments. It has been further concluded that the person having more hemoglobin (14) and higher blood pressure (120/90) may have more blood flow or mean activity (85.80). In addition, it has been also concluded that although hot and cold water treatments can be used for increment in blood flow, temperature should be retained according to need and sensitivity of the sample.
在本研究中,我们报告了手部功能血流的定性和定量生物散斑监测。首次采用基于强度的算法,即广义差分算法和我们之前提出的参数化全局平均 Fujii 算法,来分析由于不同处理(如热水和冷水处理)对手掌的影响所导致的各种生理变化,这有助于检查心血管疾病及相关疾病。此外,还首次监测了面部磨砂膏、美容霜和止痛软膏在手掌背面的应用所带来的血流变化。研究发现,在手掌背面涂抹四种美容霜,即 Fair & Lovely、Ponds White Beauty、Vicco Turmeric 和 Lotus Herbals Safe Sun 后,血流增加,Fair & Lovely 的平均血流量最高(154.87)。此外,在手掌背面涂抹止痛软膏,如 Volini、Fast Relief、Molid Gel 和 Zandu Gel 后,血流也会增加,其中 Volini 能使平均血流量最大程度增加(31.59),因此可以被认为是这四种软膏中最好的一种。研究还得出结论,血红蛋白含量更高(14)和血压更高(120/90)的人可能具有更高的血流或平均活动水平(85.80)。此外,虽然热水和冷水处理可以增加血流,但应根据样本的需要和敏感性来保留温度。