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X射线傅里叶叠层成像术

X-ray Fourier ptychography.

作者信息

Wakonig Klaus, Diaz Ana, Bonnin Anne, Stampanoni Marco, Bergamaschi Anna, Ihli Johannes, Guizar-Sicairos Manuel, Menzel Andreas

机构信息

Paul Scherrer Institute, Forschungsstrasse 111, 5232 Villigen PSI, Switzerland.

ETH and University of Zürich, Institute for Biomedical Engineering, 8093 Zürich, Switzerland.

出版信息

Sci Adv. 2019 Feb 1;5(2):eaav0282. doi: 10.1126/sciadv.aav0282. eCollection 2019 Feb.

Abstract

To a large extent, the performance of imaging systems is determined by their objectives, which affect properties as varied as collection efficiency, resolving power, and image distortions. Such limitations can be addressed by so-called aperture synthesis, a technique used, for instance, in radar, astronomy, and, increasingly, microscopy. Here, we apply such techniques to x-ray imaging and demonstrate how Fourier ptychography can be used at transmission x-ray microscopes to increase resolution, provide quantitative absorption and phase contrast, and allow for corrections of lens aberrations. We anticipate that such methods will find common and frequent applications, alleviating a number of limitations imposed by x-ray optical elements, offering an alternative approach to phase contrast imaging, and providing novel opportunities to mitigate radiation damage.

摘要

在很大程度上,成像系统的性能取决于其物镜,物镜会影响诸如收集效率、分辨能力和图像畸变等多种特性。这些限制可以通过所谓的孔径合成来解决,该技术例如用于雷达、天文学,并且越来越多地用于显微镜学。在此,我们将此类技术应用于X射线成像,并展示了如何在透射X射线显微镜中使用傅里叶叠层成像术来提高分辨率、提供定量吸收和相位对比度,并校正透镜像差。我们预计此类方法将得到广泛且频繁的应用,减轻X射线光学元件所带来的一些限制,提供一种相位对比度成像的替代方法,并为减轻辐射损伤提供新的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13a4/6358315/5c6bdf8d28b1/aav0282-F1.jpg

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