School of Computer Science & Technology, Beijing Institute of Technology, 5 South Zhongguancun Street, Beijing, 100081, China.
School of Optics and Electronics & Technology, Beijing Institute of Technology, 5 South Zhongguancun Street, Beijing, 100081, China.
BMC Bioinformatics. 2019 Dec 2;20(Suppl 16):587. doi: 10.1186/s12859-019-3069-x.
Malignant liver tumor is one of the main causes of human death. In order to help physician better diagnose and make personalized treatment schemes, in clinical practice, it is often necessary to segment and visualize the liver tumor from abdominal computed tomography images. Due to the large number of slices in computed tomography sequence, developing an automatic and reliable segmentation method is very favored by physicians. However, because of the noise existed in the scan sequence and the similar pixel intensity of liver tumors with their surrounding tissues, besides, the size, position and shape of tumors also vary from one patient to another, automatic liver tumor segmentation is still a difficult task.
We perform the proposed algorithm to the Liver Tumor Segmentation Challenge dataset and evaluate the segmentation results. Experimental results reveal that the proposed method achieved an average Dice score of 68.4% for tumor segmentation by using the designed network, and ASD, MSD, VOE and RVD improved from 27.8 to 21, 147 to 124, 0.52 to 0.46 and 0.69 to 0.73, respectively after performing adversarial training strategy, which proved the effectiveness of the proposed method.
The testing results show that the proposed method achieves improved performance, which corroborated the adversarial training based strategy can achieve more accurate and robustness results on liver tumor segmentation task.
恶性肝肿瘤是人类死亡的主要原因之一。为了帮助医生更好地诊断和制定个性化的治疗方案,在临床实践中,通常需要从腹部计算机断层扫描图像中分割和可视化肝肿瘤。由于计算机断层扫描序列中的切片数量众多,开发一种自动且可靠的分割方法非常受医生的青睐。然而,由于扫描序列中的噪声以及肝肿瘤与其周围组织的像素强度相似,此外,肿瘤的大小、位置和形状也因患者而异,因此自动肝肿瘤分割仍然是一项具有挑战性的任务。
我们将所提出的算法应用于肝肿瘤分割挑战赛数据集,并评估了分割结果。实验结果表明,所提出的方法使用设计的网络实现了平均为 68.4%的肿瘤分割 Dice 评分,并且在进行对抗训练策略后,ASD、MSD、VOE 和 RVD 分别从 27.8 降低到 21、147 降低到 124、0.52 降低到 0.46 和 0.69 升高到 0.73,证明了所提出方法的有效性。
测试结果表明,所提出的方法在性能上有所提高,这证实了基于对抗训练的策略可以在肝肿瘤分割任务中获得更准确和稳健的结果。