Salouti Ramin, Bagheri Mansoureh, Shamsi Anis, Zamani Mohammad
Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Salouti Cornea Research Center, Salouti Eye Clinic, Shiraz, Iran.
J Ophthalmic Vis Res. 2020 Feb 2;15(1):24-31. doi: 10.18502/jovr.v15i1.5936. eCollection 2020 Jan-Mar.
To evaluate corneal biomechanics using Corvis ST in healthy eyes from Iranian keratorefractive surgery candidates.
In this prospective consecutive observational case series, the intraocular pressure (IOP), central corneal thickness (CCT), and biomechanical properties of 1,304 eyes from 652 patients were evaluated using Corvis ST. Keratometric readings and manifest refraction were also recorded.
The mean ( SD) age of participants was 28 5 years, and 31.7% were male. The mean spherical equivalent refraction was -3.50 1.57 diopters (D), the mean IOP was 16.8 2.9 mmHg, and the mean CCT was 531 31 m for the right eye. The respective means ( SD) corneal biomechanical parameters of the right eye were as follows: first applanation time: 7.36 0.39 milliseconds (ms); first applanation length: 1.82 0.22 mm; velocity in: 0.12 0.04 m/s; second applanation time: 20.13 0.48 ms; second applanation length: 1.34 0.55 mm; velocity out: -0.67 0.17 m/s; total time: 16.84 0.64 ms; deformation amplitude: 1.05 0.10 mm; peak distance: 4.60 1.01 mm; and concave radius of curvature: 7.35 1.39 mm. In the linear regression analysis, IOP exhibited a statistically significant association with the first and second applanation times, total time, velocity in, peak distance, deformation amplitude, and concave radius of curvature.
Our study results can be used as a reference for the interpretation of Corvis ST parameters in healthy refractive surgery candidates in the Iranian population. Our results confirmed that IOP is a major determinant of Corvis parameters.
使用Corvis ST评估伊朗角膜屈光手术候选者健康眼睛的角膜生物力学。
在这个前瞻性连续观察病例系列中，使用Corvis ST评估了652例患者的1304只眼睛的眼内压（IOP）、中央角膜厚度（CCT）和生物力学特性。还记录了角膜曲率读数和明显验光结果。
参与者的平均（±标准差）年龄为28±5岁，男性占31.7%。右眼的平均等效球镜度为-3.50±1.57屈光度（D），平均IOP为16.8±2.9 mmHg，平均CCT为531±31μm。右眼的相应平均（±标准差）角膜生物力学参数如下：首次压平时间：7.36±0.39毫秒（ms）；首次压平长度：1.82±0.22毫米；向内速度：0.12±0.04米/秒；第二次压平时间：20.13±0.48 ms；第二次压平长度：1.34±0.55毫米；向外速度：-0.67±0.17米/秒；总时间：16.84±0.64 ms；变形幅度：1.05±0.10毫米；峰值距离：4.60±1.01毫米；以及凹面曲率半径：7.35±1.39毫米。在线性回归分析中，IOP与首次和第二次压平时间、总时间、向内速度、峰值距离、变形幅度和凹面曲率半径表现出统计学上的显著关联。
我们的研究结果可作为解释伊朗人群健康屈光手术候选者Corvis ST参数的参考。我们的结果证实IOP是Corvis参数的主要决定因素。
