Mutalik Chinmaya, Wang Di-Yan, Krisnawati Dyah Ika, Jazidie Achmad, Yougbare Sibidou, Kuo Tsung-Rong
International Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan.
Department of Chemistry, Tunghai University, Taichung 40704, Taiwan.
Nanomaterials (Basel). 2020 Mar 30;10(4):643. doi: 10.3390/nano10040643.
An outbreak of a bacterial contagion is a critical threat for human health worldwide. Recently, light-activated heterostructured nanomaterials (LAHNs) have shown potential as antibacterial agents, owing to their unique structural and optical properties. Many investigations have revealed that heterostructured nanomaterials are potential antibacterial agents under light irradiation. In this review, we summarize recent developments of light-activated antibacterial agents using heterostructured nanomaterials and specifically categorized those agents based on their various light harvesters. The detailed antibacterial mechanisms are also addressed. With the achievements of LAHNs as antibacterial agents, we further discuss the challenges and opportunities for their future clinical applications.
细菌传染病的爆发对全球人类健康构成了严重威胁。最近，光激活异质结构纳米材料（LAHNs）因其独特的结构和光学特性，已显示出作为抗菌剂的潜力。许多研究表明，异质结构纳米材料在光照下是潜在的抗菌剂。在这篇综述中，我们总结了使用异质结构纳米材料的光激活抗菌剂的最新进展，并根据其各种光捕获剂对这些抗菌剂进行了具体分类。还阐述了详细的抗菌机制。基于LAHNs作为抗菌剂所取得的成果，我们进一步讨论了其未来临床应用面临的挑战和机遇。
