Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong, Agricultural University, Wuhan, Hubei 430070, China.
Beijing Enhalor Int'l Tech Co., Ltd., Beijing 100081, China.
Poult Sci. 2020 Apr;99(4):2026-2032. doi: 10.1016/j.psj.2019.11.017. Epub 2020 Feb 7.
Yeast culture (YC) positively affects the performance of laying hens. The purpose of the present study was to explore the underlying mechanism for the YC-mediated performance improvement. Sixty 67-week-old Hy-Line Brown laying hens were randomly allocated into 2 experimental groups with 5 replicates of 6 birds each. One group was fed a control diet, whereas the other received the control diet supplemented with YC at 3.0 g/kg; treatment lasted for 8 wk. The results showed that dietary YC supplementation increased (P < 0.05) the total egg weight (11.2-13.6%) and egg-laying rate (13.0-13.5%) but decreased (P < 0.05) the feed/egg ratio by 9.3 to 11.0% during weeks 5 to 6 and 7 to 8 compared with the control. However, egg quality, including eggshell strength, eggshell thickness, egg weight, albumen height, egg yolk color, and Haugh unit, was not affected (P > 0.05) by YC supplementation. Furthermore, dietary YC supplementation increased (P < 0.05) chymotrypsin and ɑ-amylase activities by 54.8 to 62.5% in the duodenal chyme and reduced (P < 0.05) plasma endotoxin by 44.1%. YC dietary supplementation also upregulated (P < 0.05) the mRNA levels of intestinal barrier-related genes (occludin and claudin 1) and antimicrobial peptides genes (β-defensin 1 and 7 and cathelicidin 1 and 3) in the duodenum or jejunum compared with the control. In conclusion, dietary YC supplementation improved the performance of aged laying hens, potentially through the upregulation of intestinal digestive enzyme activities and intestinal health-related gene expression.
酵母培养物（YC）对蛋鸡产蛋性能有积极影响。本研究旨在探索 YC 介导的性能提升的潜在机制。将 60 只 67 周龄海兰褐蛋鸡随机分为 2 个实验组，每个实验组有 5 个重复，每个重复 6 只鸡。一组饲喂基础日粮，另一组在基础日粮中添加 3.0 g/kg 的 YC；试验持续 8 周。结果表明，日粮添加 YC 提高了（P＜0.05）总蛋重（11.2-13.6%）和产蛋率（13.0-13.5%），但在第 5-6 周和第 7-8 周降低了（P＜0.05）饲料/蛋比 9.3-11.0%。然而，蛋品质，包括蛋壳强度、蛋壳厚度、蛋重、蛋白高度、蛋黄颜色和哈夫单位，不受 YC 补充的影响（P＞0.05）。此外，日粮添加 YC 提高了（P＜0.05）十二指肠食糜中胰凝乳蛋白酶和α-淀粉酶活性 54.8-62.5%，降低了（P＜0.05）血浆内毒素 44.1%。YC 日粮补充还上调了（P＜0.05）十二指肠或空肠中与肠道屏障相关的基因（occludin 和 claudin 1）和抗菌肽基因（β-防御素 1 和 7 以及 cathelicidin 1 和 3）的 mRNA 水平。综上所述，日粮添加 YC 改善了老龄蛋鸡的生产性能，可能是通过上调肠道消化酶活性和肠道健康相关基因表达。
