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肠道微生物群网络中久坐与活跃生活方式转变的关键细菌。

Key Bacteria in the Gut Microbiota Network for the Transition between Sedentary and Active Lifestyle.

作者信息

Castellanos Nazareth, Diez Gustavo G, Antúnez-Almagro Carmen, Bressa Carlo, Bailén María, González-Soltero Rocío, Pérez Margarita, Larrosa Mar

机构信息

Nirakara Lab, Mindfulness and cognitive Science extraordinary Chair, Universidad Complutense de Madrid, 28223 Madrid, Spain.

Dementia Care Unit, Virgen de la Arrixaca University Hospital, 30120 Murcia, Spain.

出版信息

Microorganisms. 2020 May 24;8(5):785. doi: 10.3390/microorganisms8050785.

DOI:10.3390/microorganisms8050785
PMID:32456263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7285274/
Abstract

Physical activity modifies the gut microbiota, exerting health benefits on the host; however, the specific bacteria associated with exercise are not yet known. In this work, we propose a novel method, based on hierarchical topology, to study the differences between the microbiota of active and sedentary lifestyles, and to identify relevant bacterial taxa. Our results show that the microbiota network found in active people has a significantly higher overall efficiency and higher transmissibility rate. We also identified key bacteria in active and sedentary networks that could be involved in the conversion of an active microbial network to a sedentary microbial network and vice versa.

摘要

体育活动可改变肠道微生物群,对宿主产生健康益处;然而,与运动相关的特定细菌尚不清楚。在这项工作中,我们提出了一种基于层次拓扑的新方法,以研究活跃和久坐生活方式的微生物群之间的差异,并识别相关的细菌分类群。我们的结果表明,活跃人群中发现的微生物群网络具有显著更高的整体效率和更高的传播率。我们还确定了活跃和久坐网络中的关键细菌,它们可能参与活跃微生物网络与久坐微生物网络之间的转换,反之亦然。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea7/7285274/d97b4913cc0f/microorganisms-08-00785-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea7/7285274/865747391cd9/microorganisms-08-00785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea7/7285274/d97b4913cc0f/microorganisms-08-00785-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea7/7285274/865747391cd9/microorganisms-08-00785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea7/7285274/d97b4913cc0f/microorganisms-08-00785-g002.jpg

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The Gut Microbial Diversity of Newly Diagnosed Diabetics but Not of Prediabetics Is Significantly Different from That of Healthy Nondiabetics.新诊断糖尿病患者而非糖尿病前期患者的肠道微生物多样性与健康非糖尿病患者的存在显著差异。
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