• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

可重构多功能铁磁流体液滴机器人。

Reconfigurable multifunctional ferrofluid droplet robots.

机构信息

Physical Intelligence Department, Max Planck Institute for Intelligent Systems, Stuttgart 70569, Germany.

State Key Laboratory of Robotics and Systems, Harbin Institute of Technology, Harbin 150080, China.

出版信息

Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):27916-27926. doi: 10.1073/pnas.2016388117. Epub 2020 Oct 26.

DOI:10.1073/pnas.2016388117
PMID:33106419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7668164/
Abstract

Magnetically actuated miniature soft robots are capable of programmable deformations for multimodal locomotion and manipulation functions, potentially enabling direct access to currently unreachable or difficult-to-access regions inside the human body for minimally invasive medical operations. However, magnetic miniature soft robots are so far mostly based on elastomers, where their limited deformability prevents them from navigating inside clustered and very constrained environments, such as squeezing through narrow crevices much smaller than the robot size. Moreover, their functionalities are currently restricted by their predesigned shapes, which is challenging to be reconfigured in situ in enclosed spaces. Here, we report a method to actuate and control ferrofluid droplets as shape-programmable magnetic miniature soft robots, which can navigate in two dimensions through narrow channels much smaller than their sizes thanks to their liquid properties. By controlling the external magnetic fields spatiotemporally, these droplet robots can also be reconfigured to exhibit multiple functionalities, including on-demand splitting and merging for delivering liquid cargos and morphing into different shapes for efficient and versatile manipulation of delicate objects. In addition, a single-droplet robot can be controlled to split into multiple subdroplets and complete cooperative tasks, such as working as a programmable fluidic-mixing device for addressable and sequential mixing of different liquids. Due to their extreme deformability, in situ reconfigurability and cooperative behavior, the proposed ferrofluid droplet robots could open up a wide range of unprecedented functionalities for lab/organ-on-a-chip, fluidics, bioengineering, and medical device applications.

摘要

磁性驱动的微型软机器人能够进行可编程变形,实现多模态运动和操作功能,有可能为微创医疗手术提供直接进入人体目前无法到达或难以到达区域的途径。然而,到目前为止,磁性微型软机器人主要基于弹性体,其有限的可变形性限制了它们在密集和非常受限的环境中的导航能力,例如无法通过比机器人尺寸小得多的狭窄缝隙。此外,它们的功能目前受到其预设形状的限制,这在封闭空间中难以现场重新配置。在这里,我们报告了一种方法,可以激活和控制作为形状可编程磁性微型软机器人的铁磁流体液滴,由于其液体性质,这些液滴机器人可以在二维空间中通过比它们的尺寸小得多的狭窄通道进行导航。通过时空控制外部磁场,这些液滴机器人还可以重新配置以展示多种功能,包括按需分裂和合并以输送液体货物,并变形为不同形状以高效、多功能地操作精细物体。此外,单个液滴机器人可以被控制分裂成多个亚液滴,并完成协作任务,例如作为可编程的流体混合装置,用于不同液体的可寻址和顺序混合。由于其极端的可变形性、现场可重构性和协作行为,所提出的铁磁流体液滴机器人可以为实验室/芯片上器官、流体学、生物工程和医疗器械应用带来广泛的前所未有的功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/a01d9f0c814a/pnas.2016388117fig07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/bd427d5343f9/pnas.2016388117fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/1fc67cb69d6f/pnas.2016388117fig02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/66433e968089/pnas.2016388117fig03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/9fdf7ef3eaca/pnas.2016388117fig04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/01f315c98380/pnas.2016388117fig05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/b6650906144d/pnas.2016388117fig06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/a01d9f0c814a/pnas.2016388117fig07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/bd427d5343f9/pnas.2016388117fig01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/1fc67cb69d6f/pnas.2016388117fig02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/66433e968089/pnas.2016388117fig03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/9fdf7ef3eaca/pnas.2016388117fig04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/01f315c98380/pnas.2016388117fig05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/b6650906144d/pnas.2016388117fig06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/75df/7668164/a01d9f0c814a/pnas.2016388117fig07.jpg

相似文献

1
Reconfigurable multifunctional ferrofluid droplet robots.可重构多功能铁磁流体液滴机器人。
Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):27916-27926. doi: 10.1073/pnas.2016388117. Epub 2020 Oct 26.
2
Magnetic Liquid Metal Droplet Robot with Multifunction and High Output Force in Milli-Newton.具有多功能和毫牛顿级高输出力的磁性液态金属微滴机器人
Soft Robot. 2023 Dec;10(6):1146-1158. doi: 10.1089/soro.2022.0183. Epub 2023 Jun 16.
3
Programmable Digital Liquid Metal Droplets in Reconfigurable Magnetic Fields.可重构磁场中的可编程数字液态金属微滴
ACS Appl Mater Interfaces. 2020 Aug 19;12(33):37670-37679. doi: 10.1021/acsami.0c08179. Epub 2020 Aug 4.
4
Millirobot Based on a Phase-Transformable Magnetorheological Liquid Metal.基于相变磁流变液态金属的微型机器人。
ACS Appl Mater Interfaces. 2023 Aug 9;15(31):37658-37667. doi: 10.1021/acsami.3c06648. Epub 2023 Jul 28.
5
Programmable Morphing Hydrogels for Soft Actuators and Robots: From Structure Designs to Active Functions.可编程变形水凝胶用于软致动器和机器人:从结构设计到主动功能。
Acc Chem Res. 2022 Jun 7;55(11):1533-1545. doi: 10.1021/acs.accounts.2c00046. Epub 2022 Apr 12.
6
Exploiting ferrofluidic wetting for miniature soft machines.利用铁磁流体润湿作用实现微型软机器
Nat Commun. 2022 Dec 23;13(1):7919. doi: 10.1038/s41467-022-35646-y.
7
Individual and collective manipulation of multifunctional bimodal droplets in three dimensions.在三维空间中对多功能双峰液滴进行单独和集体操控。
Sci Adv. 2024 Jul 19;10(29):eadp1439. doi: 10.1126/sciadv.adp1439. Epub 2024 Jul 17.
8
Scale-reconfigurable miniature ferrofluidic robots for negotiating sharply variable spaces.用于在急剧变化空间中通行的可重新配置尺度的微型铁磁流体机器人。
Sci Adv. 2022 Sep 16;8(37):eabq1677. doi: 10.1126/sciadv.abq1677.
9
Liquid Metal-Elastomer Composites with Dual-Energy Transmission Mode for Multifunctional Miniature Untethered Magnetic Robots.液态金属-弹性体复合材料的双能传输模式用于多功能微型非牵引磁机器人。
Adv Sci (Weinh). 2022 Nov;9(31):e2203730. doi: 10.1002/advs.202203730. Epub 2022 Sep 5.
10
Reconfigurable Magnetic Liquid Metal Robot for High-Performance Droplet Manipulation.用于高性能液滴操控的可重构磁性液态金属机器人。
Nano Lett. 2022 Apr 13;22(7):2923-2933. doi: 10.1021/acs.nanolett.2c00100. Epub 2022 Mar 25.

引用本文的文献

1
Advances in Wettability-Engineered Open Planar-Surface Droplet Manipulation.润湿性工程化开放平面表面液滴操纵的进展。
Micromachines (Basel). 2025 Jul 31;16(8):893. doi: 10.3390/mi16080893.
2
Magnetic Fluid-Driven Vine Robots for Minimally Invasive Tissue Biopsy Sampling.用于微创组织活检采样的磁流体驱动藤蔓机器人
Adv Intell Syst. 2025 Aug;7(8):2400827. doi: 10.1002/aisy.202400827. Epub 2025 Mar 27.
3
Adaptive Ferrofluidic Robotic System with Passive Component Activation Capabilities.具有被动组件激活能力的自适应铁磁流体机器人系统。

本文引用的文献

1
Millimeter-scale flexible robots with programmable three-dimensional magnetization and motions.具有可编程三维磁化和运动的毫米级柔性机器人。
Sci Robot. 2019 Apr 24;4(29). doi: 10.1126/scirobotics.aav4494.
2
Enzyme-powered Janus platelet cell robots for active and targeted drug delivery.酶驱动的 Janus 血小板细胞机器人用于主动和靶向药物递送。
Sci Robot. 2020 Jun 10;5(43). doi: 10.1126/scirobotics.aba6137.
3
A ferrobotic system for automated microfluidic logistics.一种用于自动化微流控物流的铁机器人系统。
Cyborg Bionic Syst. 2025 Jun 24;6:0300. doi: 10.34133/cbsystems.0300. eCollection 2025.
4
Magnetic Cell-Mimetic Droplet Microrobots with Division and Exocytosis Capabilities.具有分裂和胞吐能力的磁性细胞模拟液滴微机器人
Research (Wash D C). 2025 Jun 3;8:0730. doi: 10.34133/research.0730. eCollection 2025.
5
Ferrofluid droplet generation on a zero-thickness nozzle by a magnetic field using a wedge-shaped functional surface.利用具有楔形功能表面的磁场在零厚度喷嘴上产生铁磁流体微滴。
PLoS One. 2025 May 23;20(5):e0321099. doi: 10.1371/journal.pone.0321099. eCollection 2025.
6
Particle-armored liquid robots.粒子装甲液体机器人
Sci Adv. 2025 Mar 21;11(12):eadt5888. doi: 10.1126/sciadv.adt5888.
7
Heterogeneous multiple soft millirobots in three-dimensional lumens.三维管腔中的异质多软微型机器人
Sci Adv. 2024 Nov 8;10(45):eadq1951. doi: 10.1126/sciadv.adq1951. Epub 2024 Nov 6.
8
Wearable and Implantable Soft Robots.可穿戴和可植入的软体机器人。
Chem Rev. 2024 Oct 23;124(20):11585-11636. doi: 10.1021/acs.chemrev.4c00513. Epub 2024 Oct 11.
9
Versatile, modular, and customizable magnetic solid-droplet systems.多功能、模块化且可定制的磁性固体微滴系统。
Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2405095121. doi: 10.1073/pnas.2405095121. Epub 2024 Aug 1.
10
Individual and collective manipulation of multifunctional bimodal droplets in three dimensions.在三维空间中对多功能双峰液滴进行单独和集体操控。
Sci Adv. 2024 Jul 19;10(29):eadp1439. doi: 10.1126/sciadv.adp1439. Epub 2024 Jul 17.
Sci Robot. 2020 Feb 26;5(39). doi: 10.1126/scirobotics.aba4411.
4
Reprogrammable Ferromagnetic Domains for Reconfigurable Soft Magnetic Actuators.用于可重构软磁致动器的可重新编程铁磁畴
Nano Lett. 2020 Jul 8;20(7):5185-5192. doi: 10.1021/acs.nanolett.0c01418. Epub 2020 Jun 9.
5
Liquid flow and control without solid walls.无固体壁的液体流动与控制。
Nature. 2020 May;581(7806):58-62. doi: 10.1038/s41586-020-2254-4. Epub 2020 May 6.
6
Programmable droplet manipulation by a magnetic-actuated robot.通过磁驱动机器人进行可编程液滴操纵。
Sci Adv. 2020 Feb 14;6(7):eaay5808. doi: 10.1126/sciadv.aay5808. eCollection 2020 Feb.
7
Bioinspired underwater locomotion of light-driven liquid crystal gels.受生物启发的光驱动液晶凝胶水下运动。
Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5125-5133. doi: 10.1073/pnas.1917952117. Epub 2020 Feb 24.
8
Droplets as Carriers for Flexible Electronic Devices.作为柔性电子器件载体的液滴
Adv Sci (Weinh). 2019 Oct 30;6(24):1901862. doi: 10.1002/advs.201901862. eCollection 2019 Dec.
9
Flexible Ferrofluids: Design and Applications.柔性铁磁流体:设计与应用。
Adv Mater. 2019 Dec;31(51):e1903497. doi: 10.1002/adma.201903497. Epub 2019 Oct 3.
10
Reconfigurable ferromagnetic liquid droplets.可重构铁磁液滴。
Science. 2019 Jul 19;365(6450):264-267. doi: 10.1126/science.aaw8719.